Research advancements in pharmaceutical sciences have led to the development of new
strategies in drug delivery to anterior segment. Designing a new delivery system that can …

Cytomegalovirus retinitis (CMVR) is a severe, vision-threatening disease that primarily
affects immunosuppressed patients. CMVR is the most common ocular opportunistic …

Retinal diseases, including age-related macular degeneration (AMD) and diabetic
retinopathy (DR) are the leading causes of blindness in adults over the age of 50 years in …

Sodium dependent multivitamin transporter (SMVT; product of the SLC5A6 gene) is an
important transmembrane protein responsible for translocation of vitamins and other …

Cytomegalovirus (CMV) retinitis is a vision-threatening disease that principally afflicts
immunosuppressed patients. For the management of the disease, Ganciclovir (GCV) is …

Although the eye is an accessible organ for direct drug application, ocular drug delivery
remains a major challenge due to multiple barriers within the eye. Key barriers include static …

Nanomicelles are self-assembling nanosized (usually with particle size within a range of 10
to 100 nm) colloidal dispersions with a hydrophobic core and hydrophilic shell [12]. These …

Polymers have long been employed as carriers of choice for efficient delivery of therapeutic
agents. Several block copolymers including triblock copolymers have been designed using …

We present here the first published use of letermovir for the treatment of resistant
cytomegalovirus (CMV) in a pediatric patient. A 14-year-old girl underwent a double …

Necrotising retinitis is a rare ocular infection that historically led to high rates of visual
morbidity. While acute retinal necrosis occurs in immunocompetent patients, the majority of …