The mammary gland: basic structure and molecular signaling during development

SK Biswas, S Banerjee, GW Baker, CY Kuo… - International Journal of …, 2022 - mdpi.com
The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

Motile and non‐motile cilia in human pathology: from function to phenotypes

HM Mitchison, EM Valente - The Journal of pathology, 2017 - Wiley Online Library
Ciliopathies are inherited human disorders caused by both motile and non‐motile cilia
dysfunction that form an important and rapidly expanding disease category. Ciliopathies are …

The primary cilium: a signalling centre during vertebrate development

SC Goetz, KV Anderson - Nature Reviews Genetics, 2010 - nature.com
The primary cilium has recently stepped into the spotlight, as a flood of data show that this
organelle has crucial roles in vertebrate development and human genetic diseases. Cilia …

The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex

E Taverna, M Götz, WB Huttner - Annual review of cell and …, 2014 - annualreviews.org
Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Switching on cilia: transcriptional networks regulating ciliogenesis

SP Choksi, G Lauter, P Swoboda, S Roy - Development, 2014 - journals.biologists.com
Cilia play many essential roles in fluid transport and cellular locomotion, and as sensory
hubs for a variety of signal transduction pathways. Despite having a conserved basic …

The regulation of cilium assembly and disassembly in development and disease

L Wang, BD Dynlacht - Development, 2018 - journals.biologists.com
The primary cilium is an antenna-like organelle assembled on most types of quiescent and
differentiated mammalian cells. This immotile structure is essential for interpreting …

FGF signalling: diverse roles during early vertebrate embryogenesis

K Dorey, E Amaya - Development, 2010 - journals.biologists.com
Fibroblast growth factor (FGF) signalling has been implicated during several phases of early
embryogenesis, including the patterning of the embryonic axes, the induction and/or …

Regulation of the length of neuronal primary cilia and its potential effects on signalling

V Macarelli, E Leventea, FT Merkle - Trends in cell biology, 2023 - cell.com
Primary cilia protrude from most vertebrate cell bodies and act as specialized 'signalling
antennae'that can substantially lengthen or retract in minutes to hours in response to specific …

The choroid plexus and cerebrospinal fluid: emerging roles in development, disease, and therapy

MK Lehtinen, CS Bjornsson, SM Dymecki… - Journal of …, 2013 - Soc Neuroscience
Although universally recognized as the source of cerebrospinal fluid (CSF), the choroid
plexus (ChP) has been one of the most understudied tissues in neuroscience. The reasons …

TGF-β family signaling in early vertebrate development

J Zinski, B Tajer, MC Mullins - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
TGF-β family ligands function in inducing and patterning many tissues of the early vertebrate
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …