[HTML][HTML] Endothelial glycocalyx
The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …
primarily conformed of glycoproteins and proteoglycans, which provide communication …
[HTML][HTML] Endothelial glycocalyx impairment in disease: focus on hyaluronan shedding
S Dogné, B Flamion - The American journal of pathology, 2020 - Elsevier
Hyaluronan (HA) is a ubiquitous glycosaminoglycan of the extracellular matrix. It is present
in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial …
in the endothelial glycocalyx covering the apical surface of endothelial cells. The endothelial …
Endothelial glycocalyx as a shield against diabetic vascular complications: involvement of hyaluronan and hyaluronidases
S Dogné, B Flamion, N Caron - Arteriosclerosis, thrombosis, and …, 2018 - Am Heart Assoc
The endothelial glycocalyx (EG), which covers the apical surface of the endothelial cells and
floats into the lumen of the vessels, is a key player in vascular integrity and cardiovascular …
floats into the lumen of the vessels, is a key player in vascular integrity and cardiovascular …
[HTML][HTML] The glycocalyx and its role in vascular physiology and vascular related diseases
Purpose In 2007 the two senior authors wrote a review on the structure and function of the
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
endothelial glycocalyx layer (Weinbaum in Annu Rev Biomed Eng 9: 121–167, 2007). Since …
Glomerular endothelial mitochondrial dysfunction is essential and characteristic of diabetic kidney disease susceptibility
H Qi, G Casalena, S Shi, L Yu, K Ebefors, Y Sun… - Diabetes, 2017 - Am Diabetes Assoc
The molecular signaling mechanisms between glomerular cell types during
initiation/progression of diabetic kidney disease (DKD) remain poorly understood. We …
initiation/progression of diabetic kidney disease (DKD) remain poorly understood. We …
Myeloperoxidase: A versatile mediator of endothelial dysfunction and therapeutic target during cardiovascular disease
Myeloperoxidase (MPO) is a prominent mammalian heme peroxidase and a fundamental
component of the innate immune response against microbial pathogens. In recent times …
component of the innate immune response against microbial pathogens. In recent times …
Endothelial glycocalyx as a potential theriapeutic target in organ injuries
RN Cao, L Tang, ZY Xia, R Xia - Chinese medical journal, 2019 - mednexus.org
Objective: The endothelial glycocalyx (eGC) is a dynamic and multicomponent layer of
macromolecules found at the surface of vascular endothelium, which is largely …
macromolecules found at the surface of vascular endothelium, which is largely …
[HTML][HTML] Update on the role of the endothelial glycocalyx in angiogenesis and vascular inflammation
The endothelial glycocalyx is a negatively charged, carbohydrate-rich structure that arises
from the luminal surface of the vascular endothelium and is comprised of proteoglycans …
from the luminal surface of the vascular endothelium and is comprised of proteoglycans …
[HTML][HTML] Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
Plasma hyaluronan (HA) increases systemically in type 2 diabetes (T2D) and the HA
synthesis inhibitor, 4-Methylumbelliferone, has been proposed to treat the disease …
synthesis inhibitor, 4-Methylumbelliferone, has been proposed to treat the disease …
[HTML][HTML] Modeling the glomerular filtration barrier and intercellular crosstalk
K Ebefors, E Lassén, N Anandakrishnan… - Frontiers in …, 2021 - frontiersin.org
The glomerulus is a compact cluster of capillaries responsible for blood filtration and
initiating urine production in the renal nephrons. A trilaminar structure in the capillary wall …
initiating urine production in the renal nephrons. A trilaminar structure in the capillary wall …