Periodontitis and risk of cancer: Mechanistic evidence
G Baima, M Minoli, DS Michaud, M Aimetti… - Periodontology …, 2024 - Wiley Online Library
This review aims to critically analyze the pathways of interaction and the pathogenic
mechanisms linking periodontitis and oral bacteria with the initiation/progression of cancer …
mechanisms linking periodontitis and oral bacteria with the initiation/progression of cancer …
Intestinal flora and disease mutually shape the regional immune system in the intestinal tract
B Zhou, Y Yuan, S Zhang, C Guo, X Li, G Li… - Frontiers in …, 2020 - frontiersin.org
The intestinal tract is the largest digestive organ in the human body. It is colonized by, and
consistently exposed to, a myriad of microorganisms, including bifidobacteria, lactobacillus …
consistently exposed to, a myriad of microorganisms, including bifidobacteria, lactobacillus …
Fusobacterium nucleatum and its associated systemic diseases: epidemiologic studies and possible mechanisms
Z Fan, P Tang, C Li, Q Yang, Y Xu, C Su… - Journal of Oral …, 2023 - Taylor & Francis
Background Fusobacterium nucleatum (F. nucleatum) is an anaerobic oral commensal and
the major coaggregation bridge organism linking early and late colonisers. In recent years, a …
the major coaggregation bridge organism linking early and late colonisers. In recent years, a …
Gut microbiome: a promising biomarker for immunotherapy in colorectal cancer
Research has been driven towards finding therapy predictive biomarkers for colorectal
cancer (CRC) with a special interest in studying the gut microbiome. Gut microbiome acts …
cancer (CRC) with a special interest in studying the gut microbiome. Gut microbiome acts …
Cancer-associated fibroblasts derived extracellular vesicles promote angiogenesis of colorectal adenocarcinoma cells through miR-135b-5p/FOXO1 axis
X Dai, Y Xie, M Dong - Cancer Biology & Therapy, 2022 - Taylor & Francis
Colorectal adenocarcinoma (COAD) is a prevalent malignant tumor. Cancer-associated
fibroblasts (CAFs)-derived extracellular vesicles (EVs)(CAFs-EVs) are implicated in COAD …
fibroblasts (CAFs)-derived extracellular vesicles (EVs)(CAFs-EVs) are implicated in COAD …
Microbiota-immune interactions in ulcerative colitis and colitis associated cancer and emerging microbiota-based therapies
J Popov, V Caputi, N Nandeesha… - International journal of …, 2021 - mdpi.com
Ulcerative colitis (UC) is a chronic autoimmune disorder affecting the colonic mucosa. UC is
a subtype of inflammatory bowel disease along with Crohn's disease and presents with …
a subtype of inflammatory bowel disease along with Crohn's disease and presents with …
Cancer-associated fibroblasts-derived exosomes upregulate microRNA-135b-5p to promote colorectal cancer cell growth and angiogenesis by inhibiting thioredoxin …
H Yin, S Yu, Y Xie, X Dai, M Dong, C Sheng, J Hu - Cellular Signalling, 2021 - Elsevier
Objective The role of exosomes in human cancers has been identified, while the effect of
cancer-associated fibroblasts (CAFs)-derived exosomes (CAF-exos) transmitting microRNAs …
cancer-associated fibroblasts (CAFs)-derived exosomes (CAF-exos) transmitting microRNAs …
Fusobacterium nucleatum in the Colorectum and Its Association with Cancer Risk and Survival: A Systematic Review and Meta-analysis
C Gethings-Behncke, HG Coleman, HWT Jordao… - … Biomarkers & Prevention, 2020 - AACR
Background: The gut microbiome, in particular Fusobacterium nucleatum, has been reported
to play a role in colorectal cancer development and in patient prognosis. We aimed to …
to play a role in colorectal cancer development and in patient prognosis. We aimed to …
Resolution of chronic inflammation and cancer
Chronic inflammation poses challenges to effective cancer treatment. Although anti‐
inflammatory therapies have shown short‐term benefits, their long‐term implications may be …
inflammatory therapies have shown short‐term benefits, their long‐term implications may be …
Association or causation? Exploring the oral microbiome and cancer links
Several epidemiological investigations have found associations between poor oral health
and different types of cancer, including colorectal, lung, pancreatic, and oral malignancies …
and different types of cancer, including colorectal, lung, pancreatic, and oral malignancies …