The hippocampal formation is critically involved in learning and memory and contains a
large proportion of neurons encoding aspects of the organism's spatial surroundings. In the …

Highlights•Breakthrough in automatic neuron reconstruction from VEM data will enable the
reconstruction of much larger data sets in the future.•Volume electron microscopy imaging …

The human cerebral cortex houses 1000 times more neurons than that of the cerebral cortex
of a mouse, but the possible differences in synaptic circuits between these species are still …

We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from∼
250× 140× 90 μm 3 of electron microscopic images, including pyramidal and non-pyramidal …

Dense reconstruction of synaptic connectivity requires high-resolution electron microscopy
images of entire brains and tools to efficiently trace neuronal wires across the volume. To …

To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

Brain maps are essential for integrating information and interpreting the structure-function
relationship of circuits and behavior. We aimed to generate a systematic classification of the …

INTRODUCTION The brain of mammals consists of an enormously dense network of
neuronal wires: the axons and dendrites of nerve cells. Their packing density is so high that …

To investigate circuit mechanisms underlying locomotor behavior, we used serial-section
electron microscopy (EM) to acquire a synapse-resolution dataset containing the ventral …

To fully understand how the human brain works, knowledge of its structure at high resolution
is needed. Presented here is a computationally intensive reconstruction of the ultrastructure …