Cardio-Cerebrovascular Disease is a collective term for cardiovascular disease and
cerebrovascular disease, being a serious threat to human health. A growing number of …

Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …

With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …

High-fat diet (HFD) intake provokes obesity and cardiac anomalies. Recent studies have
found that ferroptosis plays a role in HFD-induced cardiac injury, but the underlying …

Cardiovascular disease (CVD) is one of the predominant causes of death and morbidity.
Mitochondria play a key role in maintaining cardiac energy metabolism. However …

Heart aging is characterized by left ventricular hypertrophy and diastolic dysfunction, which
in turn induces a variety of cardiovascular diseases. There is still no therapeutic drug to …

Aims Cytokine storm is closely related to the initiation and progression of sepsis, and the
level of IL-6 is positively correlated with mortality and organ dysfunction. Sepsis-induced …

Cardiac fibrosis is a pathological process of multiple cardiovascular diseases, which may
lead to heart failure. Studies have shown that microRNAs (miRNAs) play critical roles in …

Heart failure development is characterized by persistent inflammation and progressive
fibrosis owing to chronic catecholamine stress. In a chronic stress state, elevated …

Aims Adiponectin has been shown to mediate cardioprotective effects and levels are
typically reduced in patients with cardiometabolic disease. Hence, there has been intense …