Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …

Bronchodilators are the cornerstone of pharmacological management of COPD. For patients
whose conditions are not sufficiently controlled by monotherapy, combining bronchodilators …

Chronic obstructive pulmonary disease (COPD) represents a significant cause of global
morbidity and mortality, with a substantial economic impact. Recent changes in the Global …

Background: A systematic review was undertaken to evaluate the efficacy of tiotropium, a
long acting anticholinergic drug, on clinical events, symptom scales, pulmonary function …

An important step in simplifying asthma and chronic obstructive pulmonary disease (COPD)
management and improving adherence with prescribed therapy is to reduce the dose …

The aim of this pilot study was to explore the relative efficacy in terms of improvement in
symptoms and lung function of combining fluticasone propionate/salmeterol combination …

Background This randomised, double-blind, placebo controlled, four-period crossover study
assessed the efficacy and safety of once-daily QVA149, a dual bronchodilator consisting of …

Severe exacerbations of chronic obstructive pulmonary disease (COPD) are morbid events
with slow recovery periods. They consume substantial healthcare resources, and they may …

After the discovery of formoterol and salmeterol, new candidates for long-acting β2-
adrenoceptor agonists (LABAs) have emerged from various companies. In particular, once …

BACKGROUND: Clinical information on 24-h spirometric efficacy of combining tiotropium
and salmeterol compared to single-agent therapy is lacking in patients with COPD …