[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

State-of-the-art materials for ultrasound-triggered drug delivery

SR Sirsi, MA Borden - Advanced drug delivery reviews, 2014 - Elsevier
Ultrasound is a unique and exciting theranostic modality that can be used to track drug
carriers, trigger drug release and improve drug deposition with high spatial precision. In this …

Nanoparticle-enhanced synergistic HIFU ablation and transarterial chemoembolization for efficient cancer therapy

Y You, Z Wang, H Ran, Y Zheng, D Wang, J Xu… - Nanoscale, 2016 - pubs.rsc.org
High-intensity focused ultrasound (HIFU) is being generally explored as a non-invasive
therapeutic modality to treat solid tumors. However, the clinical use of HIFU for large and …

Contrast-enhanced ultrasound imaging and in vivo circulatory kinetics with low-boiling-point nanoscale phase-change perfluorocarbon agents

PS Sheeran, JD Rojas, C Puett, J Hjelmquist… - Ultrasound in medicine …, 2015 - Elsevier
Many studies have explored phase-change contrast agents (PCCAs) that can be vaporized
by an ultrasonic pulse to form microbubbles for ultrasound imaging and therapy. However …

Review on acoustic droplet vaporization in ultrasound diagnostics and therapeutics

K Loskutova, D Grishenkov… - BioMed research …, 2019 - Wiley Online Library
Acoustic droplet vaporization (ADV) is the physical process in which liquid undergoes phase
transition to gas after exposure to a pressure amplitude above a certain threshold. In recent …

Role of surface tension in gas nanobubble stability under ultrasound

C Hernandez, L Nieves, AC De Leon… - … applied materials & …, 2018 - ACS Publications
Shell-stabilized gas nanobubbles have recently captured the interest of the research
community for their potential application as ultrasound contrast agents for molecular imaging …

[HTML][HTML] Effects of droplet size and perfluorocarbon boiling point on the frequency dependence of acoustic vaporization threshold

M Aliabouzar, KN Kumar, K Sarkar - The Journal of the Acoustical …, 2019 - pubs.aip.org
Phase shift liquid perfluorocarbon (PFC) droplets vaporizable by ultrasound into echogenic
microbubble above a threshold pressure, termed acoustic droplet vaporization (ADV), are …

[HTML][HTML] IR780 loaded perfluorohexane nanodroplets for efficient sonodynamic effect induced by short-pulsed focused ultrasound

N Chang, D Qin, P Wu, S Xu, S Wang, M Wan - Ultrasonics Sonochemistry, 2019 - Elsevier
Inertial cavitation is crucial for the therapeutic effects of sonodynamic. Therefore,
approaches that can induce highly efficient inertial cavitation should be of benefit for …

Heterogeneous cavitation from atomically smooth liquid–liquid interfaces

P Pfeiffer, M Shahrooz, M Tortora, CM Casciola… - Nature Physics, 2022 - nature.com
Pressure reduction in liquids may result in vaporization and bubble formation—a process
known as cavitation. It is commonly observed in hydraulic machinery, ship propellers and …

Novel method for the formation of monodisperse superheated perfluorocarbon nanodroplets as activatable ultrasound contrast agents

C de Gracia Lux, AM Vezeridis, J Lux, AM Armstrong… - RSC …, 2017 - pubs.rsc.org
Microbubble (MB) contrast agents have positively impacted the clinical ultrasound (US)
community worldwide. Their use in molecular US imaging applications has been hindered …