Adrenergic and muscarinic receptors in the human heart

OE Brodde, MC Michel - Pharmacological reviews, 1999 - ASPET
Cardiac function is controlled by the autonomic nervous system (ie, the sympathetic and the
parasympathetic nervous systems), which act via adrenoceptors and muscarinic …

Cardiac ionic currents and acute ischemia: from channels to arrhythmias

E Carmeliet - Physiological reviews, 1999 - journals.physiology.org
The aim of this review is to provide basic information on the electrophysiological changes
during acute ischemia and reperfusion from the level of ion channels up to the level of …

Muscarinic receptors in the mammalian heart

S Dhein, CJ Van Koppen, OE Brodde - Pharmacological research, 2001 - Elsevier
In the mammalian heart, cardiac function is under the control of the sympathetic and
parasympathetic nervous system. All regions of the mammalian heart are innervated by …

Bone marrow–derived regenerated cardiomyocytes (CMG cells) express functional adrenergic and muscarinic receptors

D Hakuno, K Fukuda, S Makino, F Konishi, Y Tomita… - Circulation, 2002 - Am Heart Assoc
Background—We recently reported that cardiomyocytes could be differentiated from bone
marrow mesenchymal stem cells in vitro by 5-azacytidine treatment. In native …

Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease

L Dwomoh, GS Tejeda, AB Tobin - Neuronal Signaling, 2022 - portlandpress.com
Alzheimer's disease (AD) remains a major cause of morbidity and mortality worldwide, and
despite extensive research, only a few drugs are available for management of the disease …

Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes

O Feron, TW Smith, T Michel, RA Kelly - Journal of Biological Chemistry, 1997 - ASBMB
In cardiac myocytes, as well as specialized conduction and pacemaker cells, agonist
binding to muscarinic acetylcholine receptors (mAchRs) results in the activation of several …

Transport of Ca2+ from sarcoplasmic reticulum to mitochondria in rat ventricular myocytes

VK Sharma, V Ramesh, C Franzini-Armstrong… - Journal of bioenergetics …, 2000 - Springer
Studies with electron microscopy have shown that sarcoplasmic reticulum (SR)
andmitochondria locate close to each other in cardiac muscle cells. We investigated the …

[HTML][HTML] Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes

J Hom, T Yu, Y Yoon, G Porter, SS Sheu - Biochimica et Biophysica Acta …, 2010 - Elsevier
Mitochondria are dynamic organelles that constantly undergo fission, fusion, and movement.
Increasing evidence indicates that these dynamic changes are intricately related to …

Loss of vagally mediated bradycardia and bronchoconstriction in mice lacking M2 or M3 muscarinic acetylcholine receptors

J T. Fisher, S G. Vincent, J Gomeza… - The FASEB …, 2004 - Wiley Online Library
The presence of multiple muscarinic acetylcholine receptor (mAChR) subtypes in the heart
and lung, combined with the lack of mAChR subtype‐selective ligands, have complicated …

Functional M3 muscarinic acetylcholine receptors in mammalian hearts

Z Wang, H Shi, H Wang - British journal of pharmacology, 2004 - Wiley Online Library
In contrast to most peripheral tissues where multiple subtypes of muscarinic acetylcholine
receptor (mAChR) coexist, with each of them playing its part in the orchestra of …