Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

Almost 30 years have passed since a term 'tissue engineering'was created to represent a
new concept that focuses on regeneration of neotissues from cells with the support of …

Biomaterials currently used in cardiac tissue engineering have certain limitations, such as
lack of electrical conductivity and appropriate mechanical properties, which are two …

Engineered myocardial tissues can be used to elucidate fundamental features of myocardial
biology, develop organotypic in vitro model systems, and as engineered tissue constructs for …

The current focus of medicine on molecular genetics ignores the physical basis of disease
even though many of the problems that lead to pain and morbidity, and bring patients to the …

Cardiac tissue engineering is a promising strategy to treat heart failure. Yet, several issues
remain to be resolved including the prevention of arrhythmia caused by inefficient electrical …

The use of animal models in drug discovery studies presents issues with feasibility and
ethical concerns. To address these limitations, in vitro tissue models have been developed …

Collagen gels are flowable, suggesting the possibility of an easily injectable, biocompatible
drug delivery matrix. Sustained release of therapeutic molecules from collagen matrices …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Driven by enormous clinical need, myocardial tissue engineering has become a prime focus
of research within the field of tissue engineering. Myocardial tissue engineering combines …