Mood stabilizers in psychiatric disorders and mechanisms learnt from in vitro model systems

R Nayak, I Rosh, I Kustanovich, S Stern - International journal of …, 2021 - mdpi.com
Bipolar disorder (BD) and schizophrenia are psychiatric disorders that manifest unusual
mental, behavioral, and emotional patterns leading to suffering and disability. These …

Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution

X Xiao, CY Zhang, Z Zhang, Z Hu, M Li, T Li - Molecular Psychiatry, 2022 - nature.com
Genome-wide association studies (GWASs) have revealed substantial genetic components
comprised of single nucleotide polymorphisms (SNPs) in the heritable risk of psychiatric …

Metabolic risk factors of cognitive impairment in young women with major psychiatric disorder

C Zhuo, W Liu, R Jiang, R Li, H Yu, G Chen… - Frontiers in …, 2022 - frontiersin.org
Background Cognitive performance improves clinical outcomes of patients with major
psychiatric disorder (MPD), but is impaired by hyperglycemia. Psychotropic agents often …

microRNA and the Post-Transcriptional Response to Oxidative Stress during Neuronal Differentiation: Implications for Neurodevelopmental and Psychiatric Disorders

B Khavari, MM Barnett, E Mahmoudi, MP Geaghan… - Life, 2024 - mdpi.com
Oxidative stress is one of the most important environmental exposures associated with
psychiatric disorders, but the underlying molecular mechanisms remain to be elucidated. In …

It takes two to tango: Widening our understanding of the onset of schizophrenia from a neuro-angiogenic perspective

BS Casas, D Arancibia-Altamirano… - Frontiers in Cell and …, 2022 - frontiersin.org
Schizophrenia is a chronic debilitating mental disorder characterized by perturbations in
thinking, perception, and behavior, along with brain connectivity deficiencies …

Associations of cognitive impairment in patients with schizophrenia with genetic features and with schizophrenia-related structural and functional brain changes

C Zhuo, H Tian, J Chen, Q Li, L Yang, Q Zhang… - Frontiers in …, 2022 - frontiersin.org
Cognitive impairment is highly prevalent in patients with major psychiatric disorders (MPDs),
including schizophrenia (SCZ), bipolar disorder, major depressive disorder, in whom it can …

MicroRNA 3′ ends shorten during adolescent brain maturation

KT Thomas, A Vermare, SO Egleston… - Frontiers in Molecular …, 2023 - frontiersin.org
MicroRNA (miRNA) dysregulation is well-documented in psychiatric disease, but miRNA
dynamics remain poorly understood during adolescent and early adult brain maturation …

[HTML][HTML] Significant association of variable number tandem repeat polymorphism rs58335419 in the MIR137 gene with the risk of gastric and colon cancers

P Jafari, S Baghernia… - British Journal of …, 2022 - frontierspartnerships.org
The purpose of the article: The MIR137 gene acts as a tumor-suppressor gene in colon and
gastric cancers. The aim of this study was to investigate the association of functional variable …

[HTML][HTML] Role of miRNA gene variants (miR-22 and miR-155) as the factors affecting susceptibility to panic disorder

Z Yegin, G Sarisoy, A Uzun… - Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Objective Variants within genes encoding microRNAs (miRNAs) may alter the expression of
both miRNAs and their target genes, thus contributing to the etiology of psychiatric disorders …

A Study of Association of the MIR137 VNTR rs58335419 with Schizophrenia

GI Korovaitseva, IV Oleichik, TV Lezheiko… - Russian Journal of …, 2024 - Springer
The MIR137 gene encodes microRNA-137 (miR-137), which is a brain-enriched miR that is
highly expressed in various brain regions. miR-137 has been identified as a modulator of …