Neural ensembles in navigation: From single cells to population codes

EAA Jones, LM Giocomo - Current opinion in neurobiology, 2023 - Elsevier
The brain can represent behaviorally relevant information through the firing of individual
neurons as well as the coordinated firing of ensembles of neurons. Neurons in the …

[HTML][HTML] From cell types to population dynamics: Making hippocampal manifolds physiologically interpretable

J Esparza, ER Sebastián, LM de la Prida - Current opinion in neurobiology, 2023 - Elsevier
The study of the hippocampal code is gaining momentum. While the physiological approach
targets the contribution of individual cells as determined by genetic, biophysical and circuit …

Hippocampal place codes are gated by behavioral engagement

NL Pettit, XC Yuan, CD Harvey - Nature neuroscience, 2022 - nature.com
As animals explore an environment, the hippocampus is thought to automatically form and
maintain a place code by combining sensory and self-motion signals. Instead, we observed …

A distributed and efficient population code of mixed selectivity neurons for flexible navigation decisions

S Kira, H Safaai, AS Morcos, S Panzeri… - Nature …, 2023 - nature.com
Decision-making requires flexibility to rapidly switch one's actions in response to sensory
stimuli depending on information stored in memory. We identified cortical areas and neural …

Distance-tuned neurons drive specialized path integration calculations in medial entorhinal cortex

MG Campbell, A Attinger, SA Ocko, S Ganguli… - Cell reports, 2021 - cell.com
During navigation, animals estimate their position using path integration and landmarks,
engaging many brain areas. Whether these areas follow specialized or universal cue …

Explaining heterogeneity in medial entorhinal cortex with task-driven neural networks

A Nayebi, A Attinger, M Campbell… - Advances in …, 2021 - proceedings.neurips.cc
Medial entorhinal cortex (MEC) supports a wide range of navigational and memory related
behaviors. Well-known experimental results have revealed specialized cell types in MEC …

Uncovering 2-d toroidal representations in grid cell ensemble activity during 1-d behavior

E Hermansen, DA Klindt, BA Dunn - Nature Communications, 2024 - nature.com
Minimal experiments, such as head-fixed wheel-running and sleep, offer experimental
advantages but restrict the amount of observable behavior, making it difficult to classify …

Remapping in a recurrent neural network model of navigation and context inference

IIC Low, LM Giocomo, AH Williams - Elife, 2023 - elifesciences.org
Neurons in navigational brain regions provide information about position, orientation, and
speed relative to environmental landmarks. These cells also change their firing patterns …

Learning to represent continuous variables in heterogeneous neural networks

R Darshan, A Rivkind - Cell Reports, 2022 - cell.com
Animals must monitor continuous variables such as position or head direction. Manifold
attractor networks—which enable a continuum of persistent neuronal states—provide a key …

Remapping revisited: how the hippocampus represents different spaces

AA Fenton - Nature Reviews Neuroscience, 2024 - nature.com
The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …