The neutrophil's role during health and disease
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
The neutrophil in vascular inflammation
M Phillipson, P Kubes - Nature medicine, 2011 - nature.com
Here we focus on how neutrophils have a key regulatory role in vascular inflammation.
Recent studies using advanced imaging techniques have yielded new insights into the …
Recent studies using advanced imaging techniques have yielded new insights into the …
Neutrophils and immunity: from bactericidal action to being conquered
TS Teng, A Ji, XY Ji, YZ Li - Journal of immunology research, 2017 - Wiley Online Library
The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …
primary role in the clearance of extracellular pathogens. Using the broad array of cytokines …
Age-related macular degeneration: A two-level model hypothesis
MP Rozing, JA Durhuus, MK Nielsen, Y Subhi… - Progress in retinal and …, 2020 - Elsevier
Age-related diseases, including age-related macular degeneration (AMD), are of growing
importance in a world where population ageing has become a dominant global trend …
importance in a world where population ageing has become a dominant global trend …
The pathogenesis of sepsis
DJ Stearns-Kurosawa, MF Osuchowski… - Annual review of …, 2011 - annualreviews.org
Sepsis is a serious clinical condition that represents a patient's response to a severe
infection and has a very high mortality rate. Normal immune and physiologic responses …
infection and has a very high mortality rate. Normal immune and physiologic responses …
Identification of polarized macrophage subsets in zebrafish
M Nguyen-Chi, B Laplace-Builhe, J Travnickova… - Elife, 2015 - elifesciences.org
While the mammalian macrophage phenotypes have been intensively studied in vitro, the
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
dynamic of their phenotypic polarization has never been investigated in live vertebrates. We …
Phagocytosis, degranulation and extracellular traps release by neutrophils—the current knowledge, pharmacological modulation and future prospects
B Gierlikowska, A Stachura, W Gierlikowski… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …
Molecular mechanisms regulating NETosis in infection and disease
N Branzk, V Papayannopoulos - Seminars in immunopathology, 2013 - Springer
Neutrophils are the foot soldiers of the immune system. They home in to the site of infection
and kill pathogens by phagocytosis, degranulation, and the release of web-like structures …
and kill pathogens by phagocytosis, degranulation, and the release of web-like structures …
Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps
AB Guimarães-Costa… - Proceedings of the …, 2009 - National Acad Sciences
Neutrophils are short-lived leukocytes that die by apoptosis, necrosis, and NETosis. Upon
death by NETosis, neutrophils release fibrous traps of DNA, histones, and granule proteins …
death by NETosis, neutrophils release fibrous traps of DNA, histones, and granule proteins …