Advanced MRI in cerebral small vessel disease

H Van Den Brink, FN Doubal… - International Journal of …, 2023 - journals.sagepub.com
Cerebral small vessel disease (cSVD) is a major cause of stroke and dementia. This review
summarizes recent developments in advanced neuroimaging of cSVD with a focus on …

Quantitative myelin imaging with MRI and PET: an overview of techniques and their validation status

CWJ van der Weijden, E Biondetti, IW Gutmann… - Brain, 2023 - academic.oup.com
Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Validating the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI to myelin with fluorescence microscopy

G Duhamel, VH Prevost, M Cayre, A Hertanu… - Neuroimage, 2019 - Elsevier
Abstract Inhomogeneous Magnetization Transfer (ihMT) is a development from the MT MRI
technique. IhMT can be considered as a dipolar order relaxation time (T 1D) weighted …

Whole brain inhomogeneous magnetization transfer (ihMT) imaging: sensitivity enhancement within a steady‐state gradient echo sequence

S Mchinda, G Varma, VH Prevost… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To implement, characterize, and optimize an interleaved inhomogeneous
magnetization transfer (ihMT) gradient echo sequence allowing for whole‐brain imaging …

Evaluation of the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI for multiple sclerosis

E Van Obberghen, S Mchinda… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Inhomogeneous magnetization transfer is a new
endogenous MR imaging contrast mechanism that has demonstrated high specificity for …

Microstructural correlates of 3D steady‐state inhomogeneous magnetization transfer (ihMT) in the human brain white matter assessed by myelin water imaging and …

E Ercan, G Varma, B Mädler, IE Dimitrov… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To compare the recently introduced inhomogeneous magnetization transfer (ihMT)
technique with more established MRI techniques including myelin water imaging (MWI) and …

Optimization of inhomogeneous magnetization transfer (ihMT) MRI contrast for preclinical studies using dipolar relaxation time (T1D) filtering

VH Prevost, OM Girard, S Mchinda, G Varma… - NMR in …, 2017 - Wiley Online Library
A pulsed inhomogeneous magnetization transfer (ihMT)‐prepared fast imaging sequence
was implemented at 11.75 T for preclinical studies on mouse central nervous system. A …

Low duty-cycle pulsed irradiation reduces magnetization transfer and increases the inhomogeneous magnetization transfer effect

G Varma, OM Girard, S Mchinda, VH Prevost… - Journal of Magnetic …, 2018 - Elsevier
Intense off-resonant RF irradiation can lead to saturation of the macromolecular pool
magnetization and enhance bound pool dipolar order responsible for the inhomogeneous …

Region‐specific impairment of the cervical spinal cord (SC) in amyotrophic lateral sclerosis: A preliminary study using SC templates and quantitative MRI (diffusion …

H Rasoanandrianina, AM Grapperon… - NMR in …, 2017 - Wiley Online Library
In this preliminary study, our objective was to investigate the potential of high‐resolution
anatomical imaging, diffusion tensor imaging (DTI) and conventional/inhomogeneous …

Quantitative magnetization transfer MRI unbiased by on‐resonance saturation and dipolar order contributions

L Soustelle, T Troalen, A Hertanu… - Magnetic …, 2023 - Wiley Online Library
Purpose To demonstrate the bias in quantitative MT (qMT) measures introduced by the
presence of dipolar order and on‐resonance saturation (ONRS) effects using magnetization …