Surgical margins in patients with early-stage breast cancer treated with breast conservation therapy

SE Singletary - The American journal of surgery, 2002 - Elsevier
BACKGROUND: Patients receiving breast conservation therapy have a lifelong risk of local
recurrence. To minimize this risk, surgeons have explored various approaches to examining …

Obtaining adequate surgical margins in breast-conserving therapy for patients with early-stage breast cancer: current modalities and future directions

RG Pleijhuis, M Graafland, J de Vries, J Bart… - Annals of surgical …, 2009 - Springer
Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-
conserving therapy (BCT) for early-stage breast cancer. The majority of studies report …

Intraoperative margin management in breast-conserving surgery: a systematic review of the literature

RJ Gray, BA Pockaj, E Garvey, S Blair - Annals of surgical oncology, 2018 - Springer
Background Breast surgeons have a wide variety of intraoperative techniques available to
help achieve low rates for positive margins of excision, with variable levels of evidence …

Emerging technologies for real‐time intraoperative margin assessment in future breast‐conserving surgery

AR Pradipta, T Tanei, K Morimoto, K Shimazu… - Advanced …, 2020 - Wiley Online Library
Clean surgical margins in breast‐conserving surgery (BCS) are essential for preventing
recurrence. Intraoperative pathologic diagnostic methods, such as frozen section analysis …

Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial

NMA Krekel, MH Haloua, AMFL Cardozo… - The lancet …, 2013 - thelancet.com
Background Breast-conserving surgery for palpable breast cancer is associated with tumour-
involved margins in up to 41% of cases and excessively large excision volumes. Ultrasound …

Toolbox to reduce lumpectomy reoperations and improve cosmetic outcome in breast cancer patients: the American Society of Breast Surgeons Consensus …

J Landercasper, D Attai, D Atisha, P Beitsch… - Annals of surgical …, 2015 - Springer
Background Multiple recent reports have documented significant variability of reoperation
rates after initial lumpectomy for breast cancer. To address this issue, a multidisciplinary …

Accuracy of intraoperative gross examination of surgical margin status in women undergoing partial mastectomy for breast malignancy

GC Balch, SK Mithani, JF Simpson… - The American …, 2005 - journals.sagepub.com
Margin status is an important prognostic factor for local recurrence after partial mastectomy
for breast malignancy. Options for intraoperative evaluation of margin status include gross …

A comparison of three methods for nonpalpable breast cancer excision

NMA Krekel, BM Zonderhuis, H Stockmann… - European Journal of …, 2011 - Elsevier
AIMS: To evaluate the efficacy of three methods of breast-conserving surgery (BCS) for
nonpalpable invasive breast cancer in obtaining adequate resection margins and volumes …

[HTML][HTML] Intraoperative assessment of margins in breast conserving therapy: a systematic review

K Butler-Henderson, AH Lee, RI Price, K Waring - The Breast, 2014 - Elsevier
Approximately one quarter of patients undergoing breast conserving therapy for breast
cancer will require a second operation to achieve adequate clearance of the margins. A …

Factors correlating with reexcision after breast-conserving therapy

MR Bani, MP Lux, K Heusinger, E Wenkel… - European Journal of …, 2009 - Elsevier
AIM: The aim of this study was to evaluate factors affecting the risk for reexcision following
breast-conserving surgery. Positive tumor margins are critical for local disease control …