[HTML][HTML] Mechanisms of multidrug resistance in cancer chemotherapy

K Bukowski, M Kciuk, R Kontek - International journal of molecular …, 2020 - mdpi.com
Cancer is one of the main causes of death worldwide. Despite the significant development of
methods of cancer healing during the past decades, chemotherapy still remains the main …

[HTML][HTML] Protein glycosylation and tumor microenvironment alterations driving cancer hallmarks

A Peixoto, M Relvas-Santos, R Azevedo… - Frontiers in …, 2019 - frontiersin.org
Decades of research have disclosed a plethora of alterations in protein glycosylation that
decisively impact in all stages of disease and ultimately contribute to more aggressive cell …

[HTML][HTML] Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data

Q Liu, L Fang, G Yu, D Wang, CL Xiao… - Nature communications, 2019 - nature.com
DNA base modifications, such as C5-methylcytosine (5mC) and N6-methyldeoxyadenosine
(6mA), are important types of epigenetic regulations. Short-read bisulfite sequencing and …

The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives

AK Farha, RY Gan, HB Li, DT Wu… - Critical Reviews in …, 2022 - Taylor & Francis
Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …

[HTML][HTML] Methyl donor micronutrients that modify DNA methylation and cancer outcome

AM Mahmoud, MM Ali - Nutrients, 2019 - mdpi.com
DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

[HTML][HTML] Migraine and diet

P Gazerani - Nutrients, 2020 - mdpi.com
Migraine is characterized by recurrent attacks of disabling headaches, often accompanied
by sensory and motor disturbances. Clinical manifestations of migraine are influenced by …

[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Advances in digital polymerase chain reaction (dPCR) and its emerging biomedical applications

L Cao, X Cui, J Hu, Z Li, JR Choi, Q Yang, M Lin… - Biosensors and …, 2017 - Elsevier
Since the invention of polymerase chain reaction (PCR) in 1985, PCR has played a
significant role in molecular diagnostics for genetic diseases, pathogens, oncogenes and …

[HTML][HTML] Histone modifications and non-coding RNAs: mutual epigenetic regulation and role in pathogenesis

IV Bure, MV Nemtsova, EB Kuznetsova - International Journal of …, 2022 - mdpi.com
In the last few years, more and more scientists have suggested and confirmed that
epigenetic regulators are tightly connected and form a comprehensive network of regulatory …

[HTML][HTML] Epigenetics in cancer therapy and nanomedicine

A Roberti, AF Valdes, R Torrecillas, MF Fraga… - Clinical …, 2019 - Springer
The emergence of nanotechnology applied to medicine has revolutionized the treatment of
human cancer. As in the case of classic drugs for the treatment of cancer, epigenetic drugs …