In this personalized review, the history of EEG recorded simultaneously with functional MRI
(EEG–fMRI) is summarized. A brief overview is given of the hardware development followed …

During the past decade, substantial progress has been made in delineating clinical features
of the epilepsies and the basic mechanisms responsible for these disorders. Eleven human …

As we start to fall asleep, the sense of self slackens. Images float by, and our awareness
becomes progressively absorbed in them. The impression of being a bounded individual …

Since prediction of long-term seizure outcome using preoperative diagnostic modalities
remains suboptimal in epilepsy surgery, we evaluated whether interictal spike frequency …

The science behind claims of alien encounters and visions of ghosts can be even more
fascinating than the sensationalist headlines. What leads some people to believe in the …

Malformations of cortical development (MCDs) are commonly complicated by intractable
focal epilepsy. Epileptogenesis in these disorders is not well understood and may depend …

Background The main challenge in assessing patients with epilepsy for resective surgery is
localising seizure onset. Frequently, identification of the irritative and seizure onset zones …

During human seizures, organized waves of voltage activity rapidly sweep across the cortex.
Two contradictory theories describe the source of these fast traveling waves: either a slowly …

Most research on focal epilepsy focuses on mechanisms of seizure generation in the
primary epileptic focus (EF). However, neurological deficits that are not directly linked to …

Epileptic events initiate a large focal increase in metabolism and cerebral blood flow (CBF)
to the ictal focus. In contrast, decreases in CBF have been demonstrated surrounding the …