The retina is a complex tissue with multiple cell layers that are highly ordered. Its
sophisticated structure makes it especially sensitive to external or internal perturbations that …

Mounting evidence suggests neuroinflammation is a key process in glaucoma, yet the
precise roles are not known. Understanding these complex processes, which may also be a …

Retinal degenerative diseases are major causes of vision loss and blindness worldwide and
are characterized by chronic and progressive neuronal loss. One common feature of retinal …

Although once daily anti-glaucoma drug therapy is a current clinical reality, most therapies
require multiple dosing and there is an unmet need to develop convenient, safe, and …

Glaucoma is a group of diseases involving the optic nerve and associated structures, which
is characterized by progressive visual field loss and typical changes of the optic nerve head …

The pathogenesis of glaucoma is still not fully clarified but a growing body of evidence
suggests that neuroinflammation and immune response are part of the sequence of …

Retinal ganglion cells, the neurons that selectively die in glaucoma and other optic
neuropathies, are endowed with an exceedingly active metabolism and display a particular …

Reduction of intraocular pressure (IOP) by pharmaceutical or surgical means has long been
the standard treatment for glaucoma. A number of excellent drugs are available that are …

Glaucoma is an age-related optic neuropathy involving sensitivity to ocular pressure. The
disease is now seen increasingly as one of the central nervous system, as powerful new …

Glaucoma is a multifactorial neurodegenerative disorder and one of the leading causes of
irreversible blindness globally and for which intraocular pressure is the only modifiable risk …