[HTML][HTML] Treatment strategies for cryptococcal infection: challenges, advances and future outlook
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …
The antifungal pipeline: a reality check
JR Perfect - Nature reviews Drug discovery, 2017 - nature.com
Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …
immunocompromised population of the world increases, owing partially to the increased …
Cryptococcosis
EK Maziarz, JR Perfect - Infectious disease clinics, 2016 - id.theclinics.com
Cryptococcosis is an infectious disease with worldwide distribution and wide array of clinical
presentations caused by pathogenic encapsulated yeasts in the genus Cryptococcus …
presentations caused by pathogenic encapsulated yeasts in the genus Cryptococcus …
Pulmonary cryptococcosis: a review of pathobiology and clinical aspects
F Setianingrum, R Rautemaa-Richardson… - Medical …, 2019 - academic.oup.com
Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …
[HTML][HTML] Vaccines for human fungal diseases: close but still a long way to go
Despite the substantial global burden of human fungal infections, there are no approved
fungal vaccines to protect at risk individuals. Here, we review the progress that has been …
fungal vaccines to protect at risk individuals. Here, we review the progress that has been …
[HTML][HTML] Induction of memory-like dendritic cell responses in vivo
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack
antigen specificity and be devoid of immunological memory. Strategies that can induce …
antigen specificity and be devoid of immunological memory. Strategies that can induce …
[HTML][HTML] Pathogenic fungal infection in the lung
Z Li, G Lu, G Meng - Frontiers in immunology, 2019 - frontiersin.org
Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
Antifungal drugs: New insights in research & development
The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …
rates associated with systemic infections, the low number of available antifungal classes …
[HTML][HTML] Fungal vaccines, mechanism of actions and immunology: A comprehensive review
S Nami, R Mohammadi, M Vakili, K Khezripour… - Biomedicine & …, 2019 - Elsevier
Fungal infections include a wide range of opportunistic and invasive diseases. Two of four
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …
major fatal diseases in patients with human immunodeficiency virus (HIV) infection are …