Introduction: In recent years, extensive research has been conducted on using exosomes as
biomarkers for cancer detection. Exosomes are 40–150 nm-sized extracellular vesicles …

Lung cancer remains the leading cause of cancer-related death worldwide, and the high
incidence rates are worrisome. Exosomes are a class of extracellular vesicles secreted by …

Numerous studies have shown that exosomes are closely related to the pathogenesis of
various diseases, especially cancers. Therefore, a rapid and sensitive method for exosome …

Tumor-derived exosomes can be served as a kind of promising biomarkers for early
diagnosis of cancers. Herein, a colorimetric/photothermal dual-mode exosomes sensing …

Covalent organic frameworks (COFs) have attracted more and more attention due to their
diverse structures and multifunctionality. Their unique physicochemical properties make …

Tumor-derived exosomes containing multiple proteins originating from parent cancer cells
have emerged as biomarkers for cancer diagnosis. Herein, we propose a three-dimensional …

Large contact surfaces of protein–protein interactions (PPIs) remain to be an ongoing issue
in the discovery and design of small molecule modulators. Peptides are intrinsically capable …

Hepatocellular carcinoma (HCC) was the third leading cause of cancer-related death
globally in 2020. The treatment of the disease is complex, with a high possibility of disease …

A guanidine-functionalized (GF) covalent organic framework (COF) nanocomposite has
been developed by a post-synthetic approach for specific capture and separation of …

Aims: Blood biomarkers can improve drug development for Alzheimer's disease (AD) and its
treatment. Neuron-derived extracellular vesicles (NDEVs) in plasma offer a minimally …