The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Metastasis is the overwhelming driver of cancer mortality, accounting for the majority of
cancer deaths. Many patients present with metastatic relapse years after eradication of the …

Relapse remains the major cause of mortality for patients with Acute Myeloid Leukemia
(AML). Improved tracking of minimal residual disease (MRD) holds the promise of timely …

Liquid biopsy allows for the quick and noninvasive detection of tumor-associated
components. Various liquid biopsy components, which include circulating tumor cells, tumor …

The analysis of cell-free circulating tumor DNA (ctDNA) is a very promising tool and might
revolutionize cancer care with respect to early detection, identification of minimal residual …

Background The prognostic value of circulating tumor cells (CTCs) detected with the
CellSearch System in patients with colorectal cancer (CRC) is controversial. The aim of our …

The purpose was to investigate total cell‐free DNA (cfDNA) in colorectal cancer (CRC)
patients during treatment with second‐line chemotherapy and in healthy controls and …

Pancreatic ductal adenocarcinoma (PDAC) is the most frequent pancreatic cancer type,
characterized by a dismal prognosis due to late diagnosis, frequent metastases, and limited …

The tumor microenvironment determines development and progression of many cancers.
Epithelial–mesenchymal transition (EMT) is fundamental to tumor progression and …

Background Circulating DNA can be detected and quantified in the blood of cancer patients
and used for detection of tumor‐specific genetic alterations. The clinical utility has been …