The gut microbiome as a modulator of healthy ageing
The gut microbiome is a contributory factor in ageing-related health loss and in several non-
communicable diseases in all age groups. Some age-linked and disease-linked …
communicable diseases in all age groups. Some age-linked and disease-linked …
The role of goblet cells and mucus in intestinal homeostasis
JK Gustafsson, MEV Johansson - Nature reviews Gastroenterology & …, 2022 - nature.com
The intestinal tract faces numerous challenges that require several layers of defence. The
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
tight epithelium forms a physical barrier that is further protected by a mucus layer, which …
Gut barrier disruption and chronic disease
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week
L Liberale, L Badimon, F Montecucco… - Journal of the American …, 2022 - jacc.org
Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular
disease, the leading causes of death and disability worldwide. The concept of inflamm-aging …
disease, the leading causes of death and disability worldwide. The concept of inflamm-aging …
Brain–gut–microbiome interactions in obesity and food addiction
A Gupta, V Osadchiy, EA Mayer - Nature Reviews Gastroenterology & …, 2020 - nature.com
Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …
Gut microbiota, muscle mass and function in aging: a focus on physical frailty and sarcopenia
A Ticinesi, A Nouvenne, N Cerundolo, P Catania… - Nutrients, 2019 - mdpi.com
Human gut microbiota is able to influence the host physiology by regulating multiple
processes, including nutrient absorption, inflammation, oxidative stress, immune function …
processes, including nutrient absorption, inflammation, oxidative stress, immune function …
[HTML][HTML] Gut microbiota remodeling improves natural aging-related disorders through Akkermansia muciniphila and its derived acetic acid
J Ma, Z Liu, X Gao, Y Bao, Y Hong, X He, W Zhu… - Pharmacological …, 2023 - Elsevier
Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …
Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan
J Johansen, K Atarashi, Y Arai, N Hirose… - Nature …, 2023 - nature.com
Distinct gut microbiome ecology may be implicated in the prevention of aging-related
diseases as it influences systemic immune function and resistance to infections. Yet, the viral …
diseases as it influences systemic immune function and resistance to infections. Yet, the viral …
The microbiome as a modifier of neurodegenerative disease risk
The gut microbiome is increasingly implicated in modifying susceptibility to and progression
of neurodegenerative diseases (NDs). In this review, we discuss roles for the microbiome in …
of neurodegenerative diseases (NDs). In this review, we discuss roles for the microbiome in …
Oral–gut microbiome axis in gastrointestinal disease and cancer
SY Park, BO Hwang, M Lim, SH Ok, SK Lee, KS Chun… - Cancers, 2021 - mdpi.com
Simple Summary Microbiota dysbiosis is correlated with numerous diseases in the human
body. To date, the research on the microbiome-associated diseases been focused on an …
body. To date, the research on the microbiome-associated diseases been focused on an …