Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

The recent outbreak of Corona virus SARS-CoV-2 disease COVID-19 in the China and
subsequent intermittent spread of infection to other countries has alarmed the medical and …

Antimalarial drug discovery has until recently been driven by high‐throughput phenotypic
cellular screening, allowing millions of compounds to be assayed and delivering clinical …

The novel coronavirus, SARS-CoV-2, has caused a recent pandemic called COVID-19 and
a severe health threat around the world. In the current situation, the virus is rapidly …

Abstract The Coronavirus COVID-19 Main Proteases play critical role in the propagation of
the Novel Coronavirus (COVID-19). We have applied a bioinformatics approach of drug …

Microsporidia are fungal obligate intracellular pathogens, which infect most animals and
cause microsporidiosis. Despite the serious threat that microsporidia pose to humans and …

Neglected Tropical Diseases (NTD) represent a serious threat to humans, especially for
those living in poor or developing countries. Almost one-sixth of the world population is at …

The continued toll of COVID-19 has halted the smooth functioning of civilization on a global
scale. With a limited understanding of all the essential components of viral machinery and …

Our previous work found that the clinical histone deacetylase (HDAC) inhibitor quisinostat
exhibited a significant antimalarial effect but with severe toxicity. In this work, 35 novel …

Introduction The unique physicochemical properties and chemical diversity of
organofluorine compounds have remarkably contributed for their wide utility in the area of …