The native tissues are complex structures consisting of different cell types, extracellular
matrix materials, and biomolecules. Traditional tissue engineering strategies have not been …

Negatively charged tissues are ubiquitous in the human body and are associated with a
number of common diseases yet remain an outstanding challenge for targeted drug delivery …

Tendon injuries represent a significant clinical burden on healthcare systems worldwide. As
the human population ages and the life expectancy increases, tendon injuries will become …

Tendon injury is common and debilitating, and it is associated with long-term pain and
ineffective healing. It is estimated to afflict 25% of the adult population and is often a career …

Multiple factors, such as genetic predisposition, comorbidities, anatomy, proper and prompt
diagnosis, treatment type (conservative or surgical), and patient compliance, all contribute to …

The rotator cuff consists of a cuff of soft tissue responsible for rotating the shoulder. Rotator
cuff tendon tears are responsible for a significant source of disability and pain in the adult …

Structural and hierarchical anisotropy underlies the structure-function relationship of most
living tissues. Attempts to exploit the interplay between cells and their immediate …

Tendon aging is associated with an increasing prevalence of tendon injuries and/or chronic
tendon diseases, such as tendinopathy, which affects approximately 25% of the adult …

The repair of tendon injuries is often compromised by post-operative peritendinous
adhesions. Placing a physical barrier at the interface between the tendon and the …

In this study, we intend to develop an effective tendon tissue engineering scaffold that can
provide mechanical stability and tendon regeneration ability. Using a novel electrospinning …