Matrix metalloproteinases (MMPs) are zinc‐dependent endopeptidases that were first
discovered as proteases, which target and cleave extracellular proteins. During the past 20 …

Matrix metalloproteinases (MMPs) participate from the initial phases of cancer onset to the
settlement of a metastatic niche in a second organ. Their role in cancer progression is …

Abstract Matrix metalloproteinase (MMP)-2 belongs to a family of zinc-dependent proteases
which are best known for their ability to proteolyse extracellular matrix proteins throughout …

Adaption of a single protein to perform multiple independent functions facilitates functional
plasticity of the proteome allowing a limited number of protein-coding genes to perform a …

Since its original identification as a leukocyte gelatinase/type V collagenase and tumour
type IV collagenase, gelatinase B/matrix metalloproteinase (MMP)-9 is now recognised as …

Background We determined if the sodium glucose co‐transporter 2 inhibitor empagliflozin
attenuates pressure overload‐induced heart failure in non‐diabetic mellitus mice by direct …

Three hundred years have passed since the first description of the toxicity of hydrogen
sulfide (H2S). Three papers in 1989 and 1990 described relatively high concentrations of …

Matrix metalloproteinases (MMPs), originally discovered to function in the breakdown of
extracellular matrix proteins, have gained the status of regulatory proteases in signaling …

Introduction: Diabetic retinopathy remains one of the most feared complications of diabetes.
Despite extensive research in the field, the molecular mechanism responsible for the …

Beyond the disorders recognized as mitochondrial diseases, abnormalities in function
and/or ultrastructure of mitochondria have been reported in several unrelated pathologies …