[HTML][HTML] The role of IL-6 in cancer cell invasiveness and metastasis—overview and therapeutic opportunities
M Rašková, L Lacina, Z Kejík, A Venhauerová… - Cells, 2022 - mdpi.com
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various
homeostatic and pathological processes. These activities range from regulating embryonic …
homeostatic and pathological processes. These activities range from regulating embryonic …
[HTML][HTML] The exercise IL-6 enigma in cancer
Abstract Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the
context, which we have termed the 'exercise IL-6 enigma'. IL-6 is released from skeletal …
context, which we have termed the 'exercise IL-6 enigma'. IL-6 is released from skeletal …
[HTML][HTML] Tumor evolution and chemoresistance in ovarian cancer
Abstract Development of novel strategies to overcome chemoresistance is central goal in
ovarian cancer research. Natural history of the cancer development and progression is …
ovarian cancer research. Natural history of the cancer development and progression is …
[HTML][HTML] The role of inflammation and inflammatory mediators in the development, progression, metastasis, and chemoresistance of epithelial ovarian cancer
SS Savant, S Sriramkumar, HM O'Hagan - Cancers, 2018 - mdpi.com
Inflammation plays a role in the initiation and development of many types of cancers,
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …
including epithelial ovarian cancer (EOC) and high grade serous ovarian cancer (HGSC), a …
[HTML][HTML] Ovarian cancer stem cells: still an elusive entity?
M Lupia, U Cavallaro - Molecular cancer, 2017 - Springer
The cancer stem cell (CSC) model proposes that tumor development and progression are
fueled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor …
fueled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor …
[HTML][HTML] Presence and role of stem cells in ovarian cancer
NK Suster, I Virant-Klun - World journal of stem cells, 2019 - ncbi.nlm.nih.gov
Ovarian cancer is the deadliest gynecological malignancy. It is typically diagnosed at
advanced stages of the disease, with metastatic sites disseminated widely within the …
advanced stages of the disease, with metastatic sites disseminated widely within the …
Serum IL-6 and IL-8 correlate with prognostic factors in ovarian cancer
MMM Sanguinete, PHD Oliveira… - Immunological …, 2017 - Taylor & Francis
The aim of the study was to correlate serum levels of IL-2, IL-5, IL-6, IL-8, IL-10, and TNF-α
with clinical, laboratory, and pathological prognostic factors in patients with primary ovarian …
with clinical, laboratory, and pathological prognostic factors in patients with primary ovarian …
[HTML][HTML] The transcoelomic ecosystem and epithelial ovarian cancer dissemination
SJ Ritch, CM Telleria - Frontiers in Endocrinology, 2022 - frontiersin.org
Epithelial ovarian cancer (EOC) is considered the deadliest gynecological disease and is
normally diagnosed at late stages, at which point metastasis has already occurred …
normally diagnosed at late stages, at which point metastasis has already occurred …
[HTML][HTML] Resveratrol as a tumor-suppressive nutraceutical modulating tumor microenvironment and malignant behaviors of cancer
Tumor-suppressive effects of resveratrol have been shown in various types of cancer.
However, regulation of tumor microenvironment by resveratrol is still unclear. Recent …
However, regulation of tumor microenvironment by resveratrol is still unclear. Recent …
[HTML][HTML] Activation of STAT3 and STAT5 signaling in epithelial ovarian cancer progression: mechanism and therapeutic opportunity
Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite
advances in surgical and chemotherapeutic options, most patients with advanced EOC have …
advances in surgical and chemotherapeutic options, most patients with advanced EOC have …