Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …

Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably
over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin …

Background IL-17A is a key driver of human autoimmune diseases, particularly psoriasis.
Objective We sought to determine the role of IL-17A in psoriasis pathogenesis and to identify …

Objective—Interleukin (IL)-17A is regarded as an important cytokine to drive psoriasis, an
inflammatory skin disease marked by increased cardiovascular mortality. We aimed to test …

Generalized pustular psoriasis (GPP) is a severe inflammatory skin disease characterized
by the presence of sterile pustules covering almost the entire body and systemic symptoms …

Purpose To evaluate the association of serum levels of adipokines and cytokines with
psoriasis. Materials and Methods A comprehensive literature search was performed in …

Background Tumor necrosis factor-α (TNF-α) inhibitors have been reported to induce new-
onset psoriasis. Objective To better define the demographic, clinical features, and treatment …

Generalized pustular psoriasis (GPP) and erythrodermic psoriasis (EP) are the rare and
severe subtypes of psoriasis, which are often difficult to treat. The aim of this phase 3, open …

Psoriasis is a systemic inflammatory disease associated with numerous comorbidities and a
profound impact on patients' quality of life. While its complex immune pathogenesis is still …

Background AT‐helper (Th) cell subset Th17 preferentially produces interleukin (IL)‐17 and
plays a pivotal role in the pathogenesis of psoriasis. However, the pathological roles of IL …