Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Signaling pathways and targeted therapies for psoriasis

J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …

Reactive metal boride nanoparticles trap lipopolysaccharide and peptidoglycan for bacteria-infected wound healing

Y Meng, L Chen, Y Chen, J Shi, Z Zhang… - Nature …, 2022 - nature.com
Bacteria and excessive inflammation are two main factors causing non-healing wounds.
However, current studies have mainly focused on the inhibition of bacteria survival for …

Advances in understanding the immunological pathways in psoriasis

SR Georgescu, M Tampa, C Caruntu, MI Sarbu… - International journal of …, 2019 - mdpi.com
Psoriasis vulgaris is a chronic, immune-mediated, inflammatory, polygenic skin disorder
affecting approximately 2% of the population. It has a great impact on quality of life; patients …

Unraveling the ECM-immune cell crosstalk in skin diseases

O Bhattacharjee, U Ayyangar, AS Kurbet… - Frontiers in cell and …, 2019 - frontiersin.org
The extracellular matrix (ECM) is a complex network of proteins and proteoglycans secreted
by keratinocytes, fibroblasts and immune cells. The function of the skin ECM has expanded …

Constructing multifunctional Cu single-atom nanozyme for synergistic nanocatalytic therapy-mediated multidrug-resistant bacteria infected wound healing

X Qiu, L Zhuang, J Yuan, H Wang, X Dong, S He… - Journal of Colloid and …, 2023 - Elsevier
Developing an effective strategy to combat multi-drug-resistant (MDR) bacteria and promote
wound healing without overuse of antibiotics remains an important and challenging goal …

GC-MS analysis and the effect of topical application of essential oils of Pinus canariensis C. Sm., Cupressus lusitanica Mill. and Cupressus arizonica Greene aerial …

RM Kamal, MM Sabry, AM El-Halawany… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Traditionally, Coniferous plants, in particular
Pinus and Cupressus species, have been used in the treatment of burns, skin infections, and …

Inhibition of NLRP3 inflammasome-mediated pyroptosis in macrophage by cycloastragenol contributes to amelioration of imiquimod-induced psoriasis-like skin …

G Deng, W Chen, P Wang, T Zhan, W Zheng… - International …, 2019 - Elsevier
Psoriasis is a common chronic inflammatory skin disease, and the infiltrated macrophages in
psoriatic skin lesions play a key role in the progression of this uncontrolled cutaneous …

Rutin attenuates inflammation by downregulating AGE-RAGE signaling pathway in psoriasis: Network pharmacology analysis and experimental evidence

M Wang, X Ma, C Gao, Y Luo, X Fei, Q Zheng… - International …, 2023 - Elsevier
Background Jueyin granules (JYG) is effective against psoriasis, but its utility components
are not clear. Rutin is the main monomer of JYG, its therapeutic effect and mechanism on …

The Essential Oil Derived from Perilla frutescens (L.) Britt. Attenuates Imiquimod–Induced Psoriasis-like Skin Lesions in BALB/c Mice

Y Xu, Y Shi, J Huang, H Gu, C Li, L Zhang, G Liu… - Molecules, 2022 - mdpi.com
Psoriasis is reported to be a common chronic immune-mediated skin disease characterized
by abnormal keratinocytes and cell proliferation. Perilla leaves are rich in essential oils, fatty …