The Tityus serrulatus scorpion species represents a serious human health threat to in Brazil
because it is among the animals that produces the most dangerous venoms for mammals in …

Gold nanoparticles (AuNPs) attached to the extracellular leaflet of the plasma membrane of
neurons can enable the generation of action potentials (APs) in response to brief pulses of …

Ion channels undergo major conformational changes that lead to channel opening and ion
conductance. Deciphering these structure-function relationships is paramount to …

NaV1. 3 is a subtype of the voltage-gated sodium channel family. It has been implicated in
the pathogenesis of neuropathic pain, although the contribution of this channel to neuronal …

We report the chemical synthesis of scorpion toxin Cn2, a potent and highly selective
activator of the human voltage-gated sodium channel NaV1. 6. In an attempt to decouple …

Toxin production in nematocysts by Cnidaria phylum represents an important source of
bioactive compounds. Using electrophysiology and, heterologous expression of mammalian …

A multimode responsive hypochlorite probe 1, based on Terbium (III)-1, 4, 7, 10-
tetraazacyclododecane-1, 4, 7-triacetic acid (Tb (III)-DO3A) and 4, 4-difluoro-4-bora-3a, 4a …

Voltage-gated sodium channels (NaVs) are responsible for sodium influx upon cellular
depolarization and, as such, are fundamental to action potential initiation and propagation …