Objective: To describe the evolution and clinical utility of molecular testing for thyroid
nodules and cancer achieved over the last 2 decades. Methods: Scientific reports on thyroid …

Simple Summary Only about 4% of thyroid nodules are carcinomas and require surgery.
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Importance Approximately 20% of thyroid nodules display indeterminate cytology. Molecular
testing can refine the risk of malignancy and reduce the need for diagnostic …

BACKGROUND Molecular characterization in pediatric papillary thyroid cancer (PTC),
distinct from adult PTC, is important for developing molecularly targeted therapies for …

Anaplastic thyroid cancer (ATC) and advanced differentiated thyroid cancers (DTCs) show
fatal outcomes, unlike DTCs. Here, we demonstrate mutational landscape of 27 ATCs and …

Importance BRAF V600E andTERTpromoter mutations can coexist in papillary thyroid
cancer (PTC). This genetic duet was indicated to be involved in the aggressiveness of PTC …

Background Approximately 25% of thyroid nodule fine‐needle aspirates (FNAs) have
cytology that is indeterminate for malignant disease. Accurate risk stratification of these …

Context Comprehensive genomic analysis of thyroid nodules for multiple classes of
molecular alterations detected in a large series of fine needle aspiration (FNA) samples has …

The unique oncogene duet of coexisting BRAF V600E and TERT promoter mutations are
widely found to be a robust genetic background promoting human cancer aggressiveness …