Since the discovery of triggering receptor expressed on myeloid cells (TREM)-1 in 2000,
evidence documenting the profound ability of the TREM and TREM-like receptors to regulate …

Community-acquired pneumonia (CAP) is one of the respiratory infectious diseases caused
by not only bacteria, but also viruses. Antibiotic agents are needed to treat only bacterial but …

Introduction Accurate and timely diagnosis of community-acquired bacterial infections in
patients with systemic inflammation remains challenging both for clinician and laboratory …

METHODS: We studied patients requiring mechanical ventilation for more than 48 hours
who died in the intensive care unit and whose bodies were autopsied. We evaluated 3 …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-
inflammatory innate immune reactions. While TREM-1-amplified responses likely aid an …

Acute respiratory distress syndrome (ARDS) and pneumonia are closely correlated in the
critically ill patient. Whereas ARDS is often complicated by nosocomial pneumonia …

Objective To evaluate the accuracy of the soluble triggering receptor expressed on myeloid
cells-1 (sTREM-1) as a diagnostic test for bacterial infection. Design Meta-analysis of 13 …

Biomarker host genetic signatures are considered key tools for improved early diagnosis of
tuberculosis (TB) disease (development). The analysis of gene expression changes based …

Triggering receptor expressed on myeloid cells 1 (TREM-1) is a recently discovered
molecule that is expressed on the cell surface of monocytes and neutrophils. Engagement of …

Sepsis is a common and serious complication in intensive care unit patients. An important
factor in optimizing survival rates in septic patients is the ability to start treatment early in the …