Purpose: To review selected new therapies for septic shock designed to inhibit bacterial
toxins or endogenous mediators of inflammation. Data Sources: Scientific journals, scientific …

Candida albicans, an increasingly common opportunistic pathogenic fungus, frequently
causes disease in immunodeficient but not immunocompetent hosts. Clarifying the role of …

Host resistance against infections caused by the yeast Candida albicans is mediated
predominantly by polymorphonuclear leukocytes and macrophages. Antigens of Candida …

The immunopathogenesis of invasive aspergillosis and the role played by cytokines are not
fully understood. The roles of interferon (IFN)-γ and tumor necrosis factor (TNF)-α were …

Over the last three decades, the prevalence of oropharyngeal fungal infections has
increased enormously, mainly due to an increasing population of immunocompromised …

抄録 Grifolan, GRN, is a fungal antitumor β-glucan isolated from Grifola frondosa. Various
studies suggested that the underlying mechanism of the antitumor activity of GRN is strongly …

Background: Sepsis and septic shock are still major causes of morbidity and mortality in
spite of the availability of powerful and broadly active antibiotics. Methods: A prospective …

The role of tumor necrosis factor alpha (TNF-alpha) in host defense against systemic
Candida albicans infection was evaluated in a murine model of systemic candidiasis in …

Secreted aspartic proteinases (Sap) have been described as virulence factors implicated in
the mechanisms of host colonization by the yeast Candida albicans in different types of …

Tumor necrosis factor α (TNF-α) and lymphotoxin α (LT-α) are pivotal mediators of
inflammatory responses in fungal infection diseases. We hypothesized that polymorphisms …