[HTML][HTML] Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …
New therapies for advanced thyroid cancer
D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …
Updates on the management of thyroid cancer
The diagnostic modalities, stratification tools, and treatment options for patients with thyroid
cancer have rapidly evolved since the development of the American Thyroid Association …
cancer have rapidly evolved since the development of the American Thyroid Association …
Novel targeted therapies for metastatic thyroid cancer—a comprehensive review
The knowledge on thyroid cancer biology has grown over the past decade. Thus, diagnostic
and therapeutic strategies to manage thyroid cancer are rapidly evolving. With new insights …
and therapeutic strategies to manage thyroid cancer are rapidly evolving. With new insights …
Redifferentiation of radioiodine-refractory thyroid cancers
C Buffet, J Wassermann, F Hecht… - Endocrine-Related …, 2020 - erc.bioscientifica.com
The management of radioiodine refractory thyroid cancers (RAIR TC) is challenging for the
clinician. Tyrosine kinase inhibitors classically prescribed in this setting can fail due to …
clinician. Tyrosine kinase inhibitors classically prescribed in this setting can fail due to …
Redifferentiation-facilitated radioiodine therapy in thyroid cancer
L Lamartina, N Anizan, C Dupuy… - Endocrine-Related …, 2021 - erc.bioscientifica.com
Based on experimental data, the inhibition of the MAPkinase pathway in patients with
radioiodine-refractory thyroid cancer was capable of inducing a redifferentiation. Preliminary …
radioiodine-refractory thyroid cancer was capable of inducing a redifferentiation. Preliminary …
An update of new small-molecule anticancer drugs approved from 2015 to 2020
X Liang, P Wu, Q Yang, Y Xie, C He, L Yin, Z Yin… - European Journal of …, 2021 - Elsevier
A high incidence of cancer has given rise to the development of more anti-tumor drugs. From
2015 to 2020, fifty-six new small-molecule anticancer drugs, divided into ten categories …
2015 to 2020, fifty-six new small-molecule anticancer drugs, divided into ten categories …
Standardised quantitative radioiodine SPECT/CT imaging for multicentre dosimetry trials in molecular radiotherapy
RA Gregory, I Murray, J Gear, F Leek… - Physics in Medicine …, 2019 - iopscience.iop.org
Abstract The SEL-I-METRY trial (EudraCT No 2015-002269-47) is the first multicentre trial to
investigate the role of 123 I and 131 I SPECT/CT-based tumour dosimetry to predict …
investigate the role of 123 I and 131 I SPECT/CT-based tumour dosimetry to predict …
Cellular plasticity in breast cancer progression and therapy
D Kong, CJ Hughes, HL Ford - Frontiers in molecular biosciences, 2020 - frontiersin.org
With the exception of non-melanoma skin cancer, breast cancer is the most frequently
diagnosed malignant disease among women, with the majority of mortality being attributable …
diagnosed malignant disease among women, with the majority of mortality being attributable …
Redox Homeostasis in Thyroid Cancer: Implications in Na+/I− Symporter (NIS) Regulation
J Cazarin, C Dupuy, D Pires de Carvalho - International journal of …, 2022 - mdpi.com
Radioiodine therapy (RAI) is a standard and effective therapeutic approach for differentiated
thyroid cancers (DTCs) based on the unique capacity for iodide uptake and accumulation of …
thyroid cancers (DTCs) based on the unique capacity for iodide uptake and accumulation of …