Advances and prospects of phenolic acids production, biorefinery and analysis

E Valanciene, I Jonuskiene, M Syrpas, E Augustiniene… - Biomolecules, 2020 - mdpi.com
Biotechnological production of phenolic acids is attracting increased interest due to their
superior antioxidant activity, as well as other antimicrobial, dietary, and health benefits. As …

Recent advances in the metabolic pathways and microbial production of coenzyme Q

F Pierrel, A Burgardt, JH Lee, L Pelosi… - World Journal of …, 2022 - Springer
Coenzyme Q (CoQ) serves as an electron carrier in aerobic respiration and has become an
interesting target for biotechnological production due to its antioxidative effect and benefits …

Navigating practical applications of food waste valorisation based on the effects of food waste origins and storage conditions

JH Mou, ZH Qin, YF Yang, SF Liu, W Yan… - Chemical Engineering …, 2023 - Elsevier
Food wastes used as feedstock in biorefineries are of both research and market interest for
solving related environmental issues and valorising to value-added products. However, the …

Fermentative indole production via bacterial tryptophan synthase alpha subunit and plant indole-3-glycerol phosphate lyase enzymes

L Ferrer, M Mindt, M Suarez-Diez, T Jilg… - Journal of Agricultural …, 2022 - ACS Publications
Indole is produced in nature by diverse organisms and exhibits a characteristic odor
described as animal, fecal, and floral. In addition, it contributes to the flavor in foods, and it is …

Engineered Corynebacterium glutamicum as the Platform for the Production of Aromatic Aldehydes

HS Kim, JA Choi, BY Kim, L Ferrer, JM Choi… - … in Bioengineering and …, 2022 - frontiersin.org
Aromatic aldehydes, including 4-hydroxybenzaldehyde (4-HB aldehyde), protocatechuic
(PC) aldehyde, and vanillin, are used as important flavors, fragrances, and pharmaceutical …

Protocatechuate overproduction by Corynebacterium glutamicum via simultaneous engineering of native and heterologous biosynthetic pathways

T Kogure, M Suda, K Hiraga, M Inui - Metabolic engineering, 2021 - Elsevier
Abstract Protocatechuic acid (3, 4-dihydroxybenzoic acid, PCA) is a natural bioactive
phenolic acid potentially valuable as a pharmaceutical raw material owing to its diverse …

Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies

M Li, C Liu, J Yang, R Nian, M Xian, F Li… - Biotechnology advances, 2020 - Elsevier
Recent progress in metabolic engineering and synthetic biology has enabled the production
of valuable chemicals in microbial cell factories from renewable feedstocks. High value …

Protein engineering for feedback resistance in 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase

K Jayaraman, N Trachtmann, GA Sprenger… - Applied microbiology …, 2022 - Springer
The shikimate pathway delivers aromatic amino acids (AAAs) in prokaryotes, fungi, and
plants and is highly utilized in the industrial synthesis of bioactive compounds. Carbon flow …

Engineering Corynebacterium glutamicum for de novo production of 2-phenylethanol from lignocellulosic biomass hydrolysate

N Zhu, W Xia, G Wang, Y Song, X Gao, J Liang… - … for Biofuels and …, 2023 - Springer
Background 2-Phenylethanol is a specific aromatic alcohol with a rose-like smell, which has
been widely used in the cosmetic and food industries. At present, 2-phenylethanol is mainly …

l-Serine Biosensor-Controlled Fermentative Production of l-Tryptophan Derivatives by Corynebacterium glutamicum

L Ferrer, M Elsaraf, M Mindt, VF Wendisch - Biology, 2022 - mdpi.com
Simple Summary l-tryptophan is an amino acid found in proteins. Its derivatives, such as
hydroxylated or halogenated l-tryptophans, find applications in the chemical and …