Antibodies of IgG4 subclass are exceptional players of the immune system, as they are
considered to be immunologically inert and functionally monovalent, and as such may be …

Autoimmune encephalitides, with an estimated incidence of 1.5 per million population per
year, although described only 15 years ago, have already had a remarkable impact in …

Background Immune checkpoint inhibitors (ICIs) have significantly changed the oncology
clinic in recent years, improving survival expectations in cancer patients. ICI therapy have a …

Abstract Background Anti-IgLON5 disease is a rare neurological disorder associated with
autoantibodies against the neuronal cell adhesion protein, IgLON5. Cellular investigations …

Background Circulating autoantibodies (AB) against brain-antigens, often deemed
pathological, receive increasing attention. We assessed predispositions and …

Cognitive dysfunction is a common feature of autoimmune encephalitis. Pathogenic
neuronal surface antibodies are thought to mediate distinct profiles of cognitive impairment …

The heterogeneity of autoantibody targets in autoimmune encephalitides presents a
challenge for understanding cellular and humoral pathophysiology, and the development of …

Objective The encephalitis associated with antibodies against contactin‐associated
proteinlike 2 (CASPR2) is presumably antibody‐mediated, but the antibody effects and …

Anti-contactin associated protein receptor 2 (CASPR2) encephalitis is a severe autoimmune
encephalitis with a variable clinical phenotype including behavioral abnormalities, cognitive …

Encephalitides with antibodies directed against leucine-rich glioma-inactivated 1 (LGI1) and
contactin-associated protein-like 2 (Caspr2) represent two increasingly well characterised …