The rapidly declining prevalence of Helicobacter pylori infection and widespread use of
potent anti-secretory drugs means peptic ulcer disease has become substantially less …

Peptic ulcer disease continues to be a source of significant morbidity and mortality
worldwide. Approximately two-thirds of patients found to have peptic ulcer disease are …

1 ESGE recommends in patients with acute upper gastrointestinal hemorrhage (UGIH) the
use of the Glasgow–Blatchford Score (GBS) for pre-endoscopy risk stratification. Patients …

We performed systematic reviews addressing predefined clinical questions to develop
recommendations with the GRADE approach regarding management of patients with overt …

Description: This update of the 2010 International Consensus Recommendations on the
Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding (UGIB) refines …

The risk of endoscopy in patients on antithrombotics depends on the risks of procedural
haemorrhage vs. thrombosis due to discontinuation of therapy. P2Y12 receptor antagonists …

This is the first UK national guideline to concentrate on acute lower gastrointestinal bleeding
(LGIB) and has been commissioned by the Clinical Services and Standards Committee of …

1 ESGE recommends that the initial assessment of patients presenting with acute lower
gastrointestinal bleeding should include: a history of co-morbidities and medications that …

Background The introduction of proton pump inhibitors (PPIs) into clinical practice has
revolutionized the management of acid-related diseases. Studies in primary care and …

Background Peptic ulcer disease (PUD) is a common digestive disorder, of which the
prevalence decreased in the past few decades. However, the decreasing tendency has …