Nucleic acid amplification has permeated every field in the life sciences since the
introduction of the classic polymerase chain reaction (PCR) method in 1983. Yet, despite its …

Recombinase polymerase amplification (RPA) is a highly sensitive and selective isothermal
amplification technique, operating at 37–42° C, with minimal sample preparation and …

BACKGROUND First introduced in 2006, recombinase polymerase amplification (RPA) has
stirred great interest, as evidenced by 75 publications as of October 2015, with 56 of them …

Highly infectious illness caused by pathogens is endemic especially in developing nations
where there is limited laboratory infrastructure and trained personnel. Rapid point-of-care …

Nucleic acid amplification is an essential process in biological systems. The in vitro adoption
of this process has resulted in powerful techniques that underpin modern molecular biology …

In March 2020, the SARS-CoV-2 virus outbreak was declared as a world pandemic by the
World Health Organization (WHO). The only measures for controlling the outbreak are …

Introduction Recombinase polymerase amplification (RPA) is a promising and emerging
technology for rapidly amplifying target nucleic acid from minimally processed samples and …

Isothermal molecular diagnostics are bridging the technology gap between traditional
diagnostics and polymerase chain reaction-based methods. These new techniques enable …

Recombinase polymerase amplification (RPA) technology relies on three major proteins,
recombinase proteins, single-strand binding proteins, and polymerases, to specifically …

Recombinase polymerase amplification (RPA) has been recognized as a promising
isothermal amplification method for nucleic acid detection. However, the digital format of …