Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - … and Targeted Therapy, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Improving DNA nanostructure stability: A review of the biomedical applications and approaches

M Nasiri, M Bahadorani, K Dellinger… - International Journal of …, 2024 - Elsevier
DNA's programmable, predictable, and precise self-assembly properties enable structural
DNA nanotechnology. DNA nanostructures have a wide range of applications in drug …

DNA hydrogels for bone regeneration

D Athanasiadou, N Meshry… - Proceedings of the …, 2023 - National Acad Sciences
DNA-based biomaterials have been proposed for tissue engineering approaches due to
their predictable assembly into complex morphologies and ease of functionalization. For …

Peptide functionalized DNA hydrogel enhances neuroblastoma cell growth and differentiation

P Hivare, A Gangrade, G Swarup, K Bhavsar, A Singh… - Nanoscale, 2022 - pubs.rsc.org
Designing programmable biomaterials that could act as extracellular matrices and permit
functionalization is a current need for tissue engineering advancement. DNA based …

Interpenetrating gels in binary suspensions of DNA nanostars

E Lattuada, T Pietrangeli, F Sciortino - The Journal of Chemical …, 2022 - pubs.aip.org
We experimentally investigate the equilibrium gel formation in a binary mixture of DNA
nanostars. The binding rules, encoded in the DNA sequence of the nanostar binding ends …

Multifunctional siRNA/ferrocene/cyclodextrin nanoparticles for enhanced chemodynamic cancer therapy

G Raj, DS Vasudev, S Christopher, A Babulal… - Nanoscale, 2024 - pubs.rsc.org
The therapeutic outcome of chemodynamic therapy (CDT) is greatly hindered by the
presence of oxidative damage repair proteins (MTH1) inside cancer cells. These oxidative …

G4-Quartet hydrogel loaded with doxorubicin and hemin for cascade chemodynamic therapy

G Raj, VKK Dommeti, V Pradeep, AK Veetil… - Materials Chemistry …, 2022 - pubs.rsc.org
The efficiency of CDT for cancer treatment is significantly reduced due to the low
concentration of H2O2 inside the cancer cell and the poor water solubility of the traditional …

Esterase-Responsive Floxuridine-Tethered Multifunctional Nanoparticles for Targeted Cancer Therapy

A Krishna, G Raj, SP, G Mohan, BB Aliyas… - ACS Applied Bio …, 2024 - ACS Publications
Floxuridine is a potential clinical anticancer drug for the treatment of various cancers.
However, floxuridine typically causes unfavorable side effects due to its very poor tumor …

Programmable soft DNA hydrogels stimulate cellular endocytic pathways and proliferation

A Singh, N Singh, ME Jinugu, P Thareja, D Bhatia - Biomaterials Advances, 2024 - Elsevier
Hydrogels are pivotal in tissue engineering, regenerative medicine, and drug delivery
applications. Existing hydrogel platforms are not easily customizable and often lack precise …

DNA Nanotechnology‐Based Supramolecular Assemblies for Targeted Biomedical Applications

A Singh, D Bhatia - The Chemical Record, 2022 - Wiley Online Library
DNA is a polyanionic, hydrophilic, and natural biopolymer that offers properties such as
biodegradability, biocompatibility, non‐toxicity, and non‐immunogenicity. These properties …