Comet assay: a reliable tool for the assessment of DNA damage in different models

A Dhawan, M Bajpayee, D Parmar - Cell biology and toxicology, 2009 - Springer
New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …

Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA

P Møller - Mutation research/reviews in mutation research, 2006 - Elsevier
Genotoxicity measured by the comet assay is expressed by different researchers using
parameters that are not easy to conceptualize, except for percent tail DNA (% T) or visual …

Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)

V Sharma, D Anderson, A Dhawan - Apoptosis, 2012 - Springer
The wide scale use of Zinc oxide (ZnO) nanoparticles in the world consumer market makes
human beings more prone to the exposure to ZnO nanoparticles and its adverse effects. The …

Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles

V Sharma, P Singh, AK Pandey, A Dhawan - Mutation Research/Genetic …, 2012 - Elsevier
Zinc oxide (ZnO) nanoparticles are finding applications in a wide range of products including
cosmetics, food packaging, imaging, etc. This increases the likelihood of human exposure to …

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

RK Shukla, V Sharma, AK Pandey, S Singh, S Sultana… - Toxicology in vitro, 2011 - Elsevier
Titanium dioxide nanoparticles (TiO2 NPs) are among the top five NPs used in consumer
products, paints and pharmaceutical preparations. Since, exposure to such nanoparticles is …

DNA damaging potential of zinc oxide nanoparticles in human epidermal cells

V Sharma, RK Shukla, N Saxena, D Parmar, M Das… - Toxicology letters, 2009 - Elsevier
At present, more than 20 countries worldwide are manufacturing and marketing different
varieties of nanotech-based consumer products of which cosmetics form the largest …

TiO2 nanoparticles induce oxidative DNA damage and apoptosis in human liver cells

RK Shukla, A Kumar, D Gurbani, AK Pandey… - …, 2013 - Taylor & Francis
Abstract Titanium dioxide nanoparticles (TiO2 NPs), widely used in consumer products,
paints, pharmaceutical preparations and so on, have been shown to induce cytotoxicity …

Cerium oxide nanoparticles induced toxicity in human lung cells: role of ROS mediated DNA damage and apoptosis

S Mittal, AK Pandey - BioMed research international, 2014 - Wiley Online Library
Cerium oxide nanoparticles (CeO2 NPs) have promising industrial and biomedical
applications. In spite of their applications, the toxicity of these NPs in biological/physiological …

Comparative evaluation of environmental contamination and DNA damage induced by electronic-waste in Nigeria and China

OA Alabi, AA Bakare, X Xu, B Li, Y Zhang… - Science of the total …, 2012 - Elsevier
In the last decade, China and Nigeria have been prime destinations for the world's e-waste
disposal leading to serious environmental contamination. We carried out a comparative …

Zinc oxide nanoparticle induced genotoxicity in primary human epidermal keratinocytes

V Sharma, SK Singh, D Anderson… - … of nanoscience and …, 2011 - ingentaconnect.com
Zinc oxide (ZnO) nanoparticles are widely used in cosmetics and sunscreens. Human
epidermal keratinocytes may serve as the first portal of entry for these nanoparticles either …