Preparation and bioactivity of the rare ginsenosides Rg3 and Rh2: An updated review

W Xu, W Lyu, C Duan, F Ma, X Li, D Li - Fitoterapia, 2023 - Elsevier
Ginseng, an ancient medicinal herb, is used in oriental medicine for the treatment of various
diseases. Saponins are the main bioactive components of ginseng, but the multiple glucosyl …

Production of minor ginsenoside CK from major ginsenosides by biotransformation and its advances in targeted delivery to tumor tissues using nanoformulations

M Murugesan, R Mathiyalagan, V Boopathi, BM Kong… - Nanomaterials, 2022 - mdpi.com
For over 2000 years, ginseng (roots of Panax ginseng CA Meyer) has been used as a
traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng …

β-Glucosidase and Its Application in Bioconversion of Ginsenosides in Panax ginseng

TNA Tran, JS Son, M Awais, JH Ko, DC Yang, SK Jung - Bioengineering, 2023 - mdpi.com
Ginsenosides are a group of bioactive compounds isolated from Panax ginseng.
Conventional major ginsenosides have a long history of use in traditional medicine for both …

Engineered Glycosidase for Significantly Improved Production of Naturally Rare Vina-Ginsenoside R7

R Wang, Z Pu, JJ Janke, YC Zheng… - Journal of Agricultural …, 2023 - ACS Publications
Ginsenosides are the main bioactive ingredients in plants of the genus Panax. Vina-
ginsenoside R7 (VG-R7) is one of the rare high-value ginsenosides with health benefits. The …

Classification of glycosidases that hydrolyze the specific positions and types of sugar moieties in ginsenosides

KC Shin, DK Oh - Critical reviews in biotechnology, 2016 - Taylor & Francis
Ginsenosides are the main compounds with pharmacological activities in ginseng.
Deglycosylated ginsenosides, which are more pharmacologically active than glycosylated …

Progress in the conversion of ginsenoside Rb1 into minor ginsenosides using β-glucosidases

H Zhu, R Zhang, Z Huang, J Zhou - Foods, 2023 - mdpi.com
In recent years, minor ginsenosides have received increasing attention due to their
outstanding biological activities, yet they are of extremely low content in wild ginseng …

[HTML][HTML] Ginsenosides analysis of New Zealand–grown forest Panax ginseng by LC-QTOF-MS/MS

W Chen, P Balan, DG Popovich - Journal of Ginseng Research, 2020 - Elsevier
Background Ginsenosides are the unique and bioactive components in ginseng.
Ginsenosides are affected by the growing environment and conditions. In New Zealand …

[HTML][HTML] Preparation of minor ginsenosides C-Mc, CY, F2, and CK from American ginseng PPD-ginsenoside using special ginsenosidase type-I from Aspergillus niger …

CY Liu, RX Zhou, CK Sun, YH Jin, HS Yu… - Journal of ginseng …, 2015 - Elsevier
Background Minor ginsenosides, those having low content in ginseng, have higher
pharmacological activities. To obtain minor ginsenosides, the biotransformation of American …

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review

M Peng, YX Yi, T Zhang, Y Ding, J Le - Frontiers in Pharmacology, 2018 - frontiersin.org
Panax notoginseng (Sanqi), a traditional Chinese medical drug which has been applied to
medical use for over four centuries, contains high content of dammarane-type tetracyclic …

Production of gypenoside XVII from ginsenoside Rb1 by enzymatic transformation and their anti-inflammatory activity in vitro and in vivo

K Zhou, Y Zhang, Y Zhou, M Xu, S Yu - Molecules, 2023 - mdpi.com
The enzymatic transformation of the sugar moiety of the gypenosides provides a new way to
obtain more pharmacologically active components. A gene encoding a family 1 glycosyl …