Impact of diet-modulated butyrate production on intestinal barrier function and inflammation

KE Bach Knudsen, HN Lærke, MS Hedemann… - Nutrients, 2018 - mdpi.com
A major challenge in affluent societies is the increase in disorders related to gut and
metabolic health. Chronic over nutrition by unhealthy foods high in energy, fat, and sugar …

Diet, microorganisms and their metabolites, and colon cancer

SJD O'keefe - Nature reviews Gastroenterology & hepatology, 2016 - nature.com
Colorectal cancer is one of the so-called westernized diseases and the second leading
cause of cancer death worldwide. On the basis of global epidemiological and scientific …

The role of gut microbiota in intestinal inflammation with respect to diet and extrinsic stressors

S Lobionda, P Sittipo, HY Kwon, YK Lee - Microorganisms, 2019 - mdpi.com
The gut microbiota maintains a symbiotic relationship with the host and regulates several
important functions including host metabolism, immunity, and intestinal barrier function …

Regulation of inflammation by short chain fatty acids

MAR Vinolo, HG Rodrigues, RT Nachbar, R Curi - Nutrients, 2011 - mdpi.com
The short chain fatty acids (SCFAs) acetate (C2), propionate (C3) and butyrate (C4) are the
main metabolic products of anaerobic bacteria fermentation in the intestine. In addition to …

Links between inflammatory bowel disease and chronic obstructive pulmonary disease

AL Raftery, E Tsantikos, NL Harris… - Frontiers in …, 2020 - frontiersin.org
Inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD) are
chronic inflammatory diseases of the gastrointestinal and respiratory tracts, respectively …

Dysbiosis of gut microbiota in promoting the development of colorectal cancer

S Zou, L Fang, MH Lee - Gastroenterology report, 2018 - academic.oup.com
Gastrointestinal microbiome, containing at least 100 trillion bacteria, resides in the mucosal
surface of human intestine. Recent studies show that perturbations in the microbiota may …

Oral exposure to polystyrene microplastics of mice on a normal or high-fat diet and intestinal and metabolic outcomes

T Okamura, M Hamaguchi, Y Hasegawa… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Microplastics (MPs) are small particles of plastic (≤ 5 mm in diameter). In
recent years, oral exposure to MPs in living organisms has been a cause of concern. Leaky …

Role of SCFAs in gut microbiome and glycolysis for colorectal cancer therapy

G Wang, Y Yu, YZ Wang, JJ Wang… - Journal of cellular …, 2019 - Wiley Online Library
Increased risk of colorectal cancer (CRC) is associated with altered intestinal microbiota as
well as short‐chain fatty acids (SCFAs) reduction of output The energy source of colon cells …

Natural polysaccharides exhibit anti-tumor activity by targeting gut microbiota

L Liu, M Li, M Yu, M Shen, Q Wang, Y Yu… - International journal of …, 2019 - Elsevier
Natural polysaccharides, the abundant dietary components, show potent antitumor
bioactivity in treatment and chemoprevention. Compared with traditional tumor therapy …

[HTML][HTML] Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E2 and cytokines

MA Cox, J Jackson, M Stanton… - World journal of …, 2009 - ncbi.nlm.nih.gov
AIM: To investigate the effect of short-chain fatty acids (SCFAs) on production of
prostaglandin E 2 (PGE 2), cytokines and chemokines in human monocytes. METHODS …