Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes
SR Pandi-Perumal, AS BaHammam, GM Brown… - Neurotoxicity …, 2013 - Springer
The pineal product melatonin has remarkable antioxidant properties. It is secreted during
darkness and plays a key role in various physiological responses including regulation of …
darkness and plays a key role in various physiological responses including regulation of …
Role of melatonin in neurodegenerative diseases
V Srinivasan, SR Pandi-Perumal, GJM Maestroni… - Neurotoxicity …, 2005 - Springer
The pineal product melatonin has remarkable antioxidant properties. It scavenges hydroxyl,
carbonate and various organic radicals, peroxynitrite and other reactive nitrogen species …
carbonate and various organic radicals, peroxynitrite and other reactive nitrogen species …
Hypoxia‐induced astrocytic reaction and increased vascular permeability in the rat cerebellum
C Kaur, V Sivakumar, Y Zhang, EA Ling - Glia, 2006 - Wiley Online Library
Hypoxia is an important factor linked to induction of vascular leakage and formation of brain
edema. In this connection, astrocytes associated closely with the blood vessels are deemed …
edema. In this connection, astrocytes associated closely with the blood vessels are deemed …
Blood–retinal barrier disruption and ultrastructural changes in the hypoxic retina in adult rats: the beneficial effect of melatonin administration
C Kaur, V Sivakumar, Z Yong, J Lu… - The Journal of …, 2007 - Wiley Online Library
Reactive changes in astrocytes and Müller cells in the retina of adult rats subjected to
hypoxia were investigated. Along with this, the integrity of the blood–retinal barrier (BRB) …
hypoxia were investigated. Along with this, the integrity of the blood–retinal barrier (BRB) …
Effect of melatonin on intracranial pressure and brain edema following traumatic brain injury: role of oxidative stresses
F Dehghan, MK Hadad, G Asadikram… - Archives of medical …, 2013 - Elsevier
BACKGROUND AND AIMS: Traumatic brain injury (TBI) is one of the main causes of brain
edema and increased intracranial pressure (ICP). In the clinic it is essential to limit the …
edema and increased intracranial pressure (ICP). In the clinic it is essential to limit the …
Melatonin reduces cerebral edema formation caused by transient forebrain ischemia in rats
T Kondoh, H Uneyama, H Nishino, K Torii - Life sciences, 2002 - Elsevier
Reduction of cerebral edema, an early symptom of ischemia, is one of the most important
remedies for reducing subsequent chronic neural damage in stroke. Melatonin, a metabolite …
remedies for reducing subsequent chronic neural damage in stroke. Melatonin, a metabolite …
A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a …
Background By the age of sixteen, one in five children will sustain a mild traumatic brain
injury also known as concussion. Our research found that one in seven school children with …
injury also known as concussion. Our research found that one in seven school children with …
Endogenous melatonin increases in cerebrospinal fluid of patients after severe traumatic brain injury and correlates with oxidative stress and metabolic disarray
MA Seifman, AA Adamides… - Journal of Cerebral …, 2008 - journals.sagepub.com
Oxidative stress plays a significant role in secondary damage after severe traumatic brain
injury (TBI); and melatonin exhibits both direct and indirect antioxidant effects. Melatonin …
injury (TBI); and melatonin exhibits both direct and indirect antioxidant effects. Melatonin …
RETRACTED: Melatonin renders neuroprotection by protein kinase C mediated aquaporin-4 inhibition in animal model of focal cerebral ischemia
P Bhattacharya, AK Pandey, S Paul, R Patnaik - 2014 - Elsevier
Panels from Figures 2a and 3a appear similar to panels from Figures 2A and 3A of the
article that the authors et al. have previously published in PLoS One 8 (9)(2013) e73481 …
article that the authors et al. have previously published in PLoS One 8 (9)(2013) e73481 …
Measurement of serum melatonin in intensive care unit patients: changes in traumatic brain injury, trauma, and medical conditions
MA Seifman, K Gomes, PN Nguyen, M Bailey… - Frontiers in …, 2014 - frontiersin.org
Melatonin is an endogenous hormone mainly produced by the pineal gland whose
dysfunction leads to abnormal sleeping patterns. Changes in melatonin have been reported …
dysfunction leads to abnormal sleeping patterns. Changes in melatonin have been reported …