The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Over the last two decades, a large number of non-communicable/chronic disorders reached
an epidemic level on a global scale such as diabetes mellitus type 2, cardio-vascular …

We normally live in symbiosis with∼ 1013 bacteria present in the colon. Among the several
mechanisms maintaining the bacteria/host balance, there is limited understanding of the …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

The thin layer of tears covering the ocular surface are a complex body fluid containing
thousands of molecules of varied form and function of several origins. In this review, we …

High-sensitivity glycan profiling providing detailed structural information is very important in
the search for glycan disease markers. By combining a straight-forward and fast preparation …

Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are
also present in saliva. This highlights that saliva can be used for clinical applications just as …

Structural analysis of complex mixtures of oligosaccharides using tandem mass
spectrometry is regularly complicated by the presence of a multitude of structural isomers …

Liquid chromatography (LC)–mass spectrometry (MS) has developed into an invaluable
technology for the analysis of protein glycosylation. This review focuses on the recent …