Frontiers in cancer immunotherapy—a symposium report

J Cable, B Greenbaum, D Pe'er… - Annals of the New …, 2021 - Wiley Online Library
Cancer immunotherapy has dramatically changed the approach to cancer treatment. The
aim of targeting the immune system to recognize and destroy cancer cells has afforded …

Mitohormesis reprogrammes macrophage metabolism to enforce tolerance

GA Timblin, KM Tharp, B Ford, JM Winchester… - Nature …, 2021 - nature.com
Macrophages generate mitochondrial reactive oxygen species and mitochondrial reactive
electrophilic species as antimicrobials during Toll-like receptor (TLR)-dependent …

Dual G9A/EZH2 inhibition stimulates antitumor immune response in ovarian high-grade serous carcinoma

P Spiliopoulou, S Spear, H Mirza, I Garner… - Molecular cancer …, 2022 - AACR
Ovarian high-grade serous carcinoma (HGSC) prognosis correlates directly with presence of
intratumoral lymphocytes. However, cancer immunotherapy has yet to achieve meaningful …