Structural analysis of molecular materials using the pair distribution function

MW Terban, SJL Billinge - Chemical Reviews, 2021 - ACS Publications
This is a review of atomic pair distribution function (PDF) analysis as applied to the study of
molecular materials. The PDF method is a powerful approach to study short-and …

Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs

CLN Vo, C Park, BJ Lee - European journal of pharmaceutics and …, 2013 - Elsevier
Over 40% of active pharmaceutical ingredients (API) in development pipelines are poorly
water-soluble drugs which limit formulation approaches, clinical application and …

[HTML][HTML] Differential scanning calorimetry techniques: applications in biology and nanoscience

P Gill, TT Moghadam, B Ranjbar - Journal of biomolecular …, 2010 - ncbi.nlm.nih.gov
This paper reviews the best-known differential scanning calorimetries (DSCs), such as
conventional DSC, microelectromechanical systems-DSC, infrared-heated DSC, modulated …

Evaluation of amorphous solid dispersion properties using thermal analysis techniques

JA Baird, LS Taylor - Advanced drug delivery reviews, 2012 - Elsevier
Amorphous solid dispersions are an increasingly important formulation approach to improve
the dissolution rate and apparent solubility of poorly water soluble compounds. Due to their …

A systematic and robust assessment of hot-melt extrusion-based amorphous solid dispersions: Theoretical prediction to practical implementation

A Alzahrani, D Nyavanandi, P Mandati… - International Journal of …, 2022 - Elsevier
Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in
recent years, with the potential to improve the apparent solubility and, hence, the oral …

Physical stability of dry powder inhaler formulations

N Shetty, D Cipolla, H Park, QT Zhou - Expert opinion on drug …, 2020 - Taylor & Francis
ABSTRACT Introduction: Dry powder inhalers (DPIs) are popular for pulmonary drug
delivery. Various techniques have been employed to produce inhalation drug particles and …

[图书][B] Pharmaceutical stress testing: predicting drug degradation

SW Baertschi, KM Alsante, RA Reed - 2016 - books.google.com
The second edition of Pharmaceutical Stress Testing: Predicting Drug Degradation provides
a practical and scientific guide to designing, executing and interpreting stress testing studies …

Nanomilling of drugs for bioavailability enhancement: a holistic formulation-process perspective

M Li, M Azad, R Davé, E Bilgili - Pharmaceutics, 2016 - mdpi.com
Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug
delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet …

Characterization of amorphous solid dispersions: An update

X Ma, RO Williams III - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Amorphous solid dispersions (ASDs) are a promising formulation approach to improve the
solubility, dissolution rate, and bioavailability of poorly water-soluble drugs. ASDs have …

Ionic liquids then and now: from solvents to materials to active pharmaceutical ingredients

WL Hough, RD Rogers - Bulletin of the Chemical Society of …, 2007 - academic.oup.com
Ionic liquids (ILs) have evolved from salts studied primarily for their physical properties (low
melting salts which could be used as solvents) to tunable materials based upon the physical …