Synthesis and transformations of nitrones for organic synthesis

SI Murahashi, Y Imada - Chemical reviews, 2019 - ACS Publications
Nitrones are important compounds and are highly useful in many aspects. The first part
describes the methods for synthesis of nitrones, which are useful and environmentally …

Bioorthogonal reactions utilizing nitrones as versatile dipoles in cycloaddition reactions

DA Bilodeau, KD Margison, M Serhan… - Chemical …, 2021 - ACS Publications
Bioorthogonal chemical reactions have emerged as convenient and rapid methods for
incorporating unnatural functionality into living systems. Different prototype reactions have …

A review of the role of hydrogen peroxide in organic transformations

H Targhan, P Evans, K Bahrami - Journal of Industrial and Engineering …, 2021 - Elsevier
Under appropriate conditions, hydrogen peroxide is able to perform a multitude of oxidative
organic reactions in an economically, technically, and environmentally satisfying manner …

Diverse applications of nitrones for the synthesis of heterocyclic compounds

LL Anderson - Asian Journal of Organic Chemistry, 2016 - Wiley Online Library
Although best known for their [3+ 2]‐dipolar cycloaddition reactivity and use in the
preparation of isoxazolines and isoxazolidines, nitrones are versatile reagents that undergo …

Cooperative Multifunctional Catalysts for Nitrone Synthesis: Platinum Nanoclusters in Amine‐Functionalized Metal–Organic Frameworks

X Li, B Zhang, L Tang, TW Goh, S Qi… - Angewandte …, 2017 - Wiley Online Library
Nitrones are key intermediates in organic synthesis and the pharmaceutical industry. The
heterogeneous synthesis of nitrones with multifunctional catalysts is extremely attractive but …

Asymmetric nitrone synthesis via ligand-enabled copper-catalyzed cope-type hydroamination of cyclopropene with oxime

Z Li, J Zhao, B Sun, T Zhou, M Liu, S Liu… - Journal of the …, 2017 - ACS Publications
We report realization of the first enantioselective Cope-type hydroamination of oximes for
asymmetric nitrone synthesis. The ligand promoted asymmetric cyclopropene …

Trapping of Arynes with In Situ Generated Aryltrifluoromethylnitrones Enables Access to Trifluoromethylated Benzoxazolines

MF Jamali, M Ahmad, SP Chandrasekharan… - Organic …, 2023 - ACS Publications
Herein, we report a rare example of trapping arynes using in situ generated
aryltrifluoromethylnitrone to access an important class of trifluoromethylated benzoxazolines …

A visible-light-promoted aerobic C–H/C–N cleavage cascade to isoxazolidine skeletons

J Xie, Q Xue, H Jin, H Li, Y Cheng, C Zhu - Chemical Science, 2013 - pubs.rsc.org
The bicyclic isoxazolidine scaffolds are the ubiquitously recurring motifs in alkaloids. Despite
of their facile biosynthesises in nature, the laboratory synthesis of these derivatives is still …

A metal-free general procedure for oxidation of secondary amines to nitrones

C Gella, E Ferrer, R Alibés, F Busque… - The Journal of …, 2009 - ACS Publications
An efficient and metal-free protocol for direct oxidation of secondary amines to nitrones has
been developed, using Oxone in a biphasic basic medium as the sole oxidant. The method …

Synthesis, antioxidant and neuroprotective analysis of diversely functionalized α-aryl-N-alkyl nitrones as potential agents for ischemic stroke therapy

A Escobar-Peso, E Martínez-Alonso… - European Journal of …, 2024 - Elsevier
Herein, we report the synthesis, antioxidant and biological evaluation of 32 monosubstituted
α-arylnitrones derived from α-phenyl-tert-butyl nitrone (PBN) in the search for …