Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis

R Lalor, K Cwiklinski, NED Calvani, A Dorey, S Hamon… - Virulence, 2021 - Taylor & Francis
Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …

Oxidative stress in parasitic diseases—Reactive oxygen species as mediators of interactions between the host and the parasites

M Pawłowska, C Mila-Kierzenkowska, J Szczegielniak… - Antioxidants, 2023 - mdpi.com
Oxidative stress plays a significant role in the development and course of parasitic
infections, both in the attacked host organism and the parasite organism struggling to …

Complementary transcriptomic and proteomic analyses reveal the cellular and molecular processes that drive growth and development of Fasciola hepatica in the …

K Cwiklinski, MW Robinson, S Donnelly, JP Dalton - BMC genomics, 2021 - Springer
Background The major pathogenesis associated with Fasciola hepatica infection results
from the extensive tissue damage caused by the tunnelling and feeding activity of immature …

Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1

A Dorey, K Cwiklinski, J Rooney… - Frontiers in cellular …, 2021 - frontiersin.org
Trematode parasites of the genus Fasciola are the cause of liver fluke disease (fasciolosis)
in humans and their livestock. Infection of the host involves invasion through the intestinal …

Advanced oxidation protein products play critical roles in liver diseases

Y Zhao, L Zhang, X Ouyang, Z Jiang… - European Journal of …, 2019 - Wiley Online Library
There is a complex oxidant and antioxidant system that maintains the redox homoeostasis in
the liver. While suffering from exogenous or endogenous risk factors, the balance between …

[HTML][HTML] Biochemical and immunological investigation of fascioliasis in cattle in Egypt

N Nasreldin, RS Zaki - Veterinary world, 2020 - ncbi.nlm.nih.gov
Materials and Methods: A total of 226 cattle were inspected for the presence of Fasciola spp.
The liver of each cattle was examined by making several incisions for detecting adult …

Glycolipidomics of Liver Flukes and Host Tissues during Fascioliasis: Insights from Mass Spectrometry Imaging

D Luh, P Ghezellou, S Heiles, S Gramberg… - ACS Infectious …, 2024 - ACS Publications
Fascioliasis, a zoonotic disease caused by liver flukes of the genus Fasciola, poses
significant health threats to both humans and livestock. While some infections remain …

Potential effects of neonicotinoid insecticides on northern bobwhites

HM Ertl, MA Mora, DE Boellstorff… - Wildlife Society …, 2018 - Wiley Online Library
Northern bobwhite (Colinus virginianus) populations have been declining in Texas, USA, for
nearly 3 decades. Reasons for the decline are unclear; however, a variety of factors have …

Two Distinct Superoxidase Dismutases (SOD) Secreted by the Helminth Parasite Fasciola hepatica Play Roles in Defence against Metabolic and Host Immune Cell …

NED Calvani, C De Marco Verissimo, HL Jewhurst… - Antioxidants, 2022 - mdpi.com
The antioxidant superoxide dismutase (SOD) catalyses the dismutation of superoxide, a
dangerous oxygen free radical, into hydrogen peroxide and molecular oxygen. Superoxide …

Liver Proteome Alterations in Red Deer (Cervus elaphus) Infected by the Giant Liver Fluke Fascioloides magna

K Šimonji, D Konjević, M Bujanić, I Rubić, V Farkaš… - Pathogens, 2022 - mdpi.com
Liver fluke infections are recognised as diseases with worldwide distribution and
considerable veterinary and public health importance. The giant liver fluke, Fascioloides …