Fluorescent labeling of biomolecules with organic probes
MST Gonçalves - Chemical reviews, 2009 - ACS Publications
Many areas of modern technology are dependent on sensitive analytical techniques, and
this is particularly true for environmental science, medicine, pharmacy, and cellular biology …
this is particularly true for environmental science, medicine, pharmacy, and cellular biology …
Redox-based regulation of signal transduction: principles, pitfalls, and promises
YMW Janssen-Heininger, BT Mossman… - Free Radical Biology …, 2008 - Elsevier
Oxidants are produced as a by-product of aerobic metabolism, and organisms ranging from
prokaryotes to mammals have evolved with an elaborate and redundant complement of …
prokaryotes to mammals have evolved with an elaborate and redundant complement of …
Reducing acetylated tau is neuroprotective in brain injury
Traumatic brain injury (TBI) is the largest non-genetic, non-aging related risk factor for
Alzheimer's disease (AD). We report here that TBI induces tau acetylation (ac-tau) at sites …
Alzheimer's disease (AD). We report here that TBI induces tau acetylation (ac-tau) at sites …
AMPK-dependent phosphorylation of GAPDH triggers Sirt1 activation and is necessary for autophagy upon glucose starvation
Eukaryotes initiate autophagy to cope with the lack of external nutrients, which requires the
activation of the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase Sirtuin 1 …
activation of the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase Sirtuin 1 …
Bioenergetics and the formation of mitochondrial reactive oxygen species
V Adam-Vizi, C Chinopoulos - Trends in pharmacological sciences, 2006 - cell.com
The contribution of mitochondria to the manifestation of disease is ascribed largely to the
production of reactive oxygen species (ROS), which are obligatory by-products of …
production of reactive oxygen species (ROS), which are obligatory by-products of …
Inflammation and lung cancer: roles of reactive oxygen/nitrogen species
N Azad, Y Rojanasakul, V Vallyathan - Journal of Toxicology and …, 2008 - Taylor & Francis
The lung is a highly specialized organ that facilitates uptake of oxygen and release of
carbon dioxide. Due to its unique structure providing enormous surface area to outside …
carbon dioxide. Due to its unique structure providing enormous surface area to outside …
[HTML][HTML] Critical protein GAPDH and its regulatory mechanisms in cancer cells
JY Zhang, F Zhang, CQ Hong, AE Giuliano… - Cancer biology & …, 2015 - ncbi.nlm.nih.gov
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), initially identified as a
glycolytic enzyme and considered as a housekeeping gene, is widely used as an internal …
glycolytic enzyme and considered as a housekeeping gene, is widely used as an internal …
On the functional diversity of glyceraldehyde-3-phosphate dehydrogenase: biochemical mechanisms and regulatory control
MA Sirover - Biochimica et Biophysica Acta (BBA)-General Subjects, 2011 - Elsevier
Background New studies provide evidence that glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) is not simply a classical glycolytic protein of little interest. Instead …
dehydrogenase (GAPDH) is not simply a classical glycolytic protein of little interest. Instead …
GAPDH: a common enzyme with uncommon functions
C Nicholls, H Li, JP Liu - Clinical and Experimental …, 2012 - Wiley Online Library
Glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) has long been recognized as an
important enzyme for energy metabolism and the production of ATP and pyruvate through …
important enzyme for energy metabolism and the production of ATP and pyruvate through …
Novel roles for GAPDH in cell death and carcinogenesis
Growing evidence points to the fact that glucose metabolism has a central role in
carcinogenesis. Among the enzymes controlling this energy production pathway …
carcinogenesis. Among the enzymes controlling this energy production pathway …