[PDF][PDF] Design of potential vitamin-drug conjugate for enhanced anticancer activity

RP Bhole, MR Swamy, R Wavhale… - Bulletin of university …, 2022 - researchgate.net
5-Fluorouracil, a primary molecule widely used in the treatment of various cancer stages, is
rapidly metabolized to an inactive form, namely 5, 6-dihydro-5-FU and various mutational …

Assessing the Potential of Vitamin Drug Conjugate for Its Activity against Infectious Disease

RP Bhole, PC Bhondave, RV Chikhale - Russian Journal of Bioorganic …, 2024 - Springer
Objective: This study explores vitamin drug conjugates, linking drugs to targeting moieties
(Niacin and Pantothenic acid), aiming to enhance TB drug efficacy, reduce dosing …

Design and Synthesis of Folic Acid-Phytochemical Conjugates as Anti-Cancer Agents

VR Mandale, AB Thomas, PA Jadhav… - Eurasian Journal of …, 2023 - ejc.buketov.edu.kz
Cancer treatment continues to be a major challenge for the medical community mainly due
to non-specificity, leading to serious toxic effects. The use of vitamins such as folic acid and …

BULLETIN OF THE KARAGANDA UNIVERSITY. CHEMISTRY SERIES

RP Bhole, MR Swamy, R Wavhale, CG Bonde… - BULLETIN OF THE … - elibrary.ru
5-Fluorouracil, a primary molecule widely used in the treatment of various cancer stages, is
rapidly metabolized to an inactive form, namely 5, 6-dihydro-5-FU and various mutational …