[HTML][HTML] Catalase: A critical node in the regulation of cell fate
Catalase (CAT) is an extensively studied if somewhat enigmatic enzyme that is at the heart
of eukaryotic antioxidant systems with a canonical role in peroxisomal function. The CAT …
of eukaryotic antioxidant systems with a canonical role in peroxisomal function. The CAT …
[HTML][HTML] Stapled peptides inhibitors: a new window for target drug discovery
AM Ali, J Atmaj, N Van Oosterwijk, MR Groves… - Computational and …, 2019 - Elsevier
Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …
PEX5 translocation into and out of peroxisomes drives matrix protein import
ML Skowyra, TA Rapoport - Molecular cell, 2022 - cell.com
Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases.
Most peroxisomal enzymes are imported from the cytosol by the receptor PEX5, which …
Most peroxisomal enzymes are imported from the cytosol by the receptor PEX5, which …
A shared, stochastic pathway mediates exosome protein budding along plasma and endosome membranes
Exosomes are small extracellular vesicles of∼ 30 to 150 nm that are secreted by all cells,
abundant in all biofluids, and play important roles in health and disease. However, details …
abundant in all biofluids, and play important roles in health and disease. However, details …
Protein import into peroxisomes occurs through a nuclear pore–like phase
Peroxisomes are ubiquitous organelles whose dysfunction causes fatal human diseases.
Most peroxisomal proteins are imported from the cytosol in a folded state by the soluble …
Most peroxisomal proteins are imported from the cytosol in a folded state by the soluble …
TPR proteins: the versatile helix
LD D'Andrea, L Regan - Trends in biochemical sciences, 2003 - cell.com
Tetratrico peptide repeat (TPR) proteins have several interesting properties, including their
folding characteristics, modular architecture and range of binding specificities. In the past …
folding characteristics, modular architecture and range of binding specificities. In the past …
Plant catalases: peroxisomal redox guardians
While genomics and post-genomics studies have revealed that plant cell redox state is
controlled by a complex genetic network, available data mean that catalase must continue to …
controlled by a complex genetic network, available data mean that catalase must continue to …
[HTML][HTML] Peroxisome biogenesis disorders
SJ Steinberg, G Dodt, GV Raymond… - … et Biophysica Acta (BBA …, 2006 - Elsevier
Defects in PEX genes impair peroxisome assembly and multiple metabolic pathways
confined to this organelle, thus providing the biochemical and molecular bases of the …
confined to this organelle, thus providing the biochemical and molecular bases of the …
Peroxisome function, biogenesis, and dynamics in plants
Peroxisome Function, Biogenesis, and Dynamics in Plants | Plant Physiology | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …
ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins
P Puntervoll, R Linding, C Gemund… - Nucleic acids …, 2003 - academic.oup.com
Multidomain proteins predominate in eukaryotic proteomes. Individual functions assigned to
different sequence segments combine to create a complex function for the whole protein …
different sequence segments combine to create a complex function for the whole protein …